257961 Enzyme Microreactors and Their Prospective Application in CO2 Bioconversion

Wednesday, October 31, 2012: 8:30 AM
407 (Convention Center )
Man Bock Gu, College of Life Sciences and Biotechnology, Korea University, Seoul, South Korea

Enzyme Microreactors and Their Prospective Application in CO2 Bioconversion

Ee Taek Hwang, Haemin Gang, Jinyang Chung, Ji Hoon Kim, Hyun Lee, Rameshwar Tatavarty, and Man Bock Gu*

College of Life Sciences and Biotechnology, Korea University, Republic of Korea

E-mail: mbgu@korea.ac.kr

TEL: +82-2-3290-3417, FAX: +82-2-928-6050

Enzymes immobilized on nano/micro sized organic/inorganic hybrid materials have been known to be stabilized. For meeting the requirement of enzymatic processes, such as highly stabilized activity, enhanced specific activity with high enzyme loading, and easy scale up, the enzymes have been subjected to be aggregated on the surfaces of quantum dots-embedded nanofibers, entraped in calcium phosphate nanoparticles, or organic-inorganic hybrid microspheres as porous support materials for good accessibility of substrate. The successful immobilization of enzymes on these enzyme-nano/micro sized organic/inorganic hybrid materials have well been evidenced by using Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), Transmission electron microscopy (TEM), while physical characterizations such as like Dynamic light scattering (DLS), Elemental analysis (EDAX), particle size etc were done. As results, the immobilized enzymes have shown the good storage and recyclable stabilities retained in terms of its enzyme activity, in repeated usages for more than ten times. Therefore, considering CO2 enzymatic bioconversion into useful materials, this unique enzyme stabilization technology developed here is strongly considered to be a key tool for realizing enzyme-based CO2 bioconversion. An example of enzyme-based CO2 bioconversion will be presented in this talk with clear perspectives on its enzyme microreactor-based CO2 bioconversion.

REFERENCES

1. E.T. Hwang, H. Lee, J.H Kim, R. Tatavarty, M.B. Gu (2011), Journal of Materials Chemistry,21 (18), 6491 – 6493

2. E.T. Hwang+, R.Tatavarty+, H. Lee, J Kim, M.B. Gu (2011), Journal of Materials Chemistry, 21 (14), 5215-5218, (Selected on the cover page) (+equally contributed authors)


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