Interaction Between An Elastic Filament and the Vesicle Membrane

Wednesday, October 19, 2011: 4:55 PM
101 C (Minneapolis Convention Center)
Yuan-Nan Young, Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, NJ and Christopher Jacobs, Biomedical Engineering, Columbia University, New York, NY

The primary cilium is found for all non-dividing mammalian cells. Since its discover
a century ago, only recently has more understanding of the biological role
of primary cilia been gained.  In this work slender-body formulation is utilized to
describe the dynamics of the primary cilium, modeled as an elastic filament attached
to a solid wall or membrane. Comparison with the experimental data will be provided.
Coupling between the filament/membrane system and the mechanosensitive channel (MscL)
show how the primary cilium functions as a probe of the extracellular flow.

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See more of this Session: Novel Numerical Methods In Fluids
See more of this Group/Topical: Engineering Sciences and Fundamentals