Wednesday, October 19, 2011: 4:55 PM
101 C (Minneapolis Convention Center)
The primary cilium is found for all non-dividing mammalian cells. Since its discover
a century ago, only recently has more understanding of the biological role
of primary cilia been gained. In this work slender-body formulation is utilized to
describe the dynamics of the primary cilium, modeled as an elastic filament attached
to a solid wall or membrane. Comparison with the experimental data will be provided.
Coupling between the filament/membrane system and the mechanosensitive channel (MscL)
show how the primary cilium functions as a probe of the extracellular flow.