Session: Mixing and Scale-up/Scale-Down Strategies for the Production of Biopharmaceuticals (2010 Annual Meeting)

Wednesday, November 10, 2010: 12:30 PM

Grand Ballroom E (Marriott Downtown)

Description:

Mixing technology plays a critical role in a large number of steps involved in the production of biopharmaceuticals. Areas of application include fermentation and cell culture processes, recovery operations and formulations. This session encourages the submission of papers in these and related areas addressing advancement, innovation and application of the state of the art in mixing and scale-up/scale-down strategies to the challenges of development and manufacture of biopharmaceuticals.

Sponsor:

North American Mixing Forum

Co-Sponsor(s):

Pharmaceuticals (15b)

Chair:

Alvin W. Nienow
Email: A.W.Nienow@bham.ac.uk

Co-Chair:

Ashraf Amanullah
Email: amanullah.ashraf@gene.com

- indicates paper has an Extended Abstract file available on CD.

12:30 PM

(476a) Novel Stirred High-Throughput Mini-Bioreactors for Bioprocess Development: Evaluation of Scale-Down From a Typical Bench-Scale Bioreactor
Bhargavi Kondragunta, Joao Silva, Kurt A. Brorson, Antonio R. Moreira and Govind Rao

12:50 PM

(476c) Mixing Uniformity Characterization of 15K Mammalian Cell Culture Bioreactor
Mei Shao, David Lindsay, Brian Stamper, LiYing Yang, Robert Torregrossa, Bernd Schmidt, Darren Hodson, Alistair Boyds and Gavin Reynolds

1:10 PM

(476d) A Scale-Down Study of the Impact of Different Stress Parameters On the Growth and Productivity of GSCHO Cell Culture
William H. Scott, Colin R. Thomas, Chris J. Hewitt, Gareth Lewis and Alvin W. Nienow

1:30 PM

(476e) Enabling T-Flasks to Improve Bioprocess Development: A Novel Disposable Cell Culture Train From Cell Thawing to Bench-Scale
Jose R. Vallejos, Kurt A. Brorson, Antonio R. Moreira, Gary J. Lye, Martina Micheletti and Govind Rao

1:50 PM

(476f) Effect of Hydrodynamic Forces On CHO Cells Used Under Industrial Production Conditions
William H. Scott, Robert Kiss, Steven Meier, Ashraf Amanullah and Alvin Nienow

2:10 PM

(476g) Directional Oscillatory Shear Index in Orbiting Petri Dishes
Amlan Chakraborty, M. Keith Sharp, Venkatakrishna R. Jala, Haribabu Bodduluri and R. Eric Berson

See more of this Group/Topical: North American Mixing Forum

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