Session: Protein Engineering II - Techniques (2010 Annual Meeting)

Monday, November 8, 2010: 12:30 PM

255 A Room (Salt Palace Convention Center)

Description:

The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) protein engineering via directed evolution; (4) computational protein engineering and design.

Sponsor:

Bioengineering

Chair:

Inchan Kwon
Email: ik4t@virginia.edu

Co-Chair:

Danielle Tullman-Ercek
Email: dtercek@berkeley.edu

12:30 PM

(119a) An in Vitro Platform to Evolve Proteins Directly for Improved Biological Function
Bertrand H. Lui, Jennifer R. Cochran and James R. Swartz

12:50 PM

(119b) Epitope Expansion Evolution for the Affinity Maturation of Ligand-Receptor Interactions
Douglas S. Jones, Mihalis S. Kariolis and Jennifer R. Cochran

1:10 PM

(119c) Engineering High-Affinity Antibodies Using Inner Membrane Display of Translocation Intermediates
Amy J. Karlsson, Hyung-Kwon Lim, Mark A. Rocco and Matthew P. DeLisa

1:30 PM

(119d) The Deg-On System: Generation of a Cell-Based High Throughput Assay for the Screening of Proteasome Activators
Wenting Zhao and Laura Segatori

1:50 PM

Break

2:00 PM

(119e) Efficient Screening of Natural Fungal Cellobiohydrolase Genes for Desirable Mutations by SCHEMA Structure-Guided Recombination
Pete Heinzelman, Russell Komor, Arvind Kanaan, Philip Romero, Xinlin Yu, Shannon Mohler, Christopher D. Snow and Frances H. Arnold

2:20 PM

(119f) De Novo Protein Design of a Conformational Switch Between α-Helical Protein and Mixed α/β Protein
James Smadbeck, Meghan L. Bellows, Yuhong Liu and Christodoulos A. Floudas

2:40 PM

(119g) Computational Analysis of the Protein Sequence Space: A New Method to Identify Beneficial Mutations
Prabuddha Bansal, Mélanie Hall, Matthew Realff, Jay H. Lee and Andreas S. Bommarius

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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