Session: Applications of PAT in a Manufacturing Setting (2010 Annual Meeting)

Wednesday, November 10, 2010: 3:15 PM

Grand Ballroom B (Salt Palace Convention Center)

Description:

This section focuses on the use of Process Analytical Technologies to monitor, control, and gain a better understanding of Pharmaceutical manufacturing processes at commercial scales. Authors are encouraged to submit papers discussing case studies and value-added applications of PAT in manufacturing settings as well as challenges overcome and lessons learned while implementing PAT in a commercial product.

Sponsor:

Topical i : Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

Co-Sponsor(s):

Pharmaceuticals (15b)

Chair:

David Unger
Email: dunger@cephalon.com

Co-Chair:

Simon D. Fraser
Email: simon.fraser@rcpe.at

3:15 PM

Welcoming Remarks

3:40 PM

(510a) Quality-by-Design (QbD): Integration of Design of Experiments (DOE) and Real-Time PAT Monitoring for Pharmaceutical Powder Blending Process Evaluation
Huiquan Wu and Mansoor A. Khan

4:00 PM

(510b) Raman Spectroscopy Combined with Small and Wide Angle X-Ray Scattering as a Non Destructive Quality Control Tool for Powder Compression Analytics in Pharmaceutical Applications
Nicolas Heigl and Johannes G. Khinast

4:20 PM

(510c) On-Line Monitoring of Roller Compaction Ribbon Density Using NIR Spectroscopy
Ryan McCann, Ariel Muliadi, Janne Paaso, James Litster and Rodolfo Pinal

4:40 PM

(510d) Real-Time Monitoring of Pharmaceutical Manufacturing Processes with a Multiplexed Optical Fiber Probe NIR-Setup
Nikolaus Balak, Daniel M. Koller and Johannes Khinast

5:00 PM

Break

5:10 PM

(510e) On-Line Blend Monitoring of Pharmaceutical Materials Using Multiple NIR Sensors
Benoit Igne, Zhenqi Shi, Carl A. Anderson and James K. Drennen III

5:30 PM

(510f) Drying Mechanism and Aggregate Formation of API
Daniel Hsieh, Joshua Engstrom, Deniz Erdemir, Steven Chan, Steve S. Y. Wang, Shih-Ying Chang, Chiajen Lai and San Kiang

5:50 PM

(510g) Real-Time Monitoring of Continuous Processes with Spectroscopic PAT-Tools
Daniel M. Koller, Nikolaus Balak, Simon D. Fraser and Johannes G. Khinast

6:10 PM

Concluding Remarks

See more of this Group/Topical: Topical i : Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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