Temperature-Responsive and Biodegradable Highly Branched Star Dendrimer for Controlled Release of Therapeutics Across Ocular Barriers

Thursday, November 11, 2010: 4:35 PM
Canyon B (Hilton)
Xiaoxun Li, Department of Pharmaceutical Sciences, Thomas Jefferson University, Philadelphia, PA, Eun Seok Gil, Department of Surgery, Pennsylvania State University, Hershey, PA and Tao Lowe, Thomas Jefferson University, Philadelphia, PA

A highly branched start-like dendrimer with thermo-responsive and biodegradable properties is designed and synthesized by novel systhesis methods. The chemical, physical and biological properties of the dendrimer is characterized for its application to enhance drug permeability and therapeutic effects across ocular barriers and the blood brain barrier.

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See more of this Session: Bionanotechnology for Gene and Drug Delivery III
See more of this Group/Topical: Nanoscale Science and Engineering Forum