Session: Downstream Processing: Harvest/Recovery (2009 Annual Meeting)

Thursday, November 12, 2009: 8:30 AM

Delta Ballroom C (Gaylord Opryland Hotel)

Description:

This session will focus on highlighting the latest advances in downstream processing relevant to harvest/recovery operations including rapid process development, improved efficiency, cost reduction, integration of operations and handling of high titre streams. Topics to be covered include, but are not limited to: Centrifugation, filtration, adsorption, extraction, precipitation and expanded bed chromatography.

Sponsor:

Bioengineering

Co-Sponsor(s):

Pharmaceuticals (15b)

Chair:

Sanjeev Katti
Email: sanjeev.katti@genzyme.com

Co-Chair:

Nihal Tugcu
Email: nihal_tugcu@merck.com

8:30 AM

(511a) Coupling Clarification and Purification Into a Single Unit Operation for Improved High-Titer Mammalian-Based Processing
Joshua Walker and Jon Romero

8:50 AM

(511b) Process Improvement of Tangential Flow Filtration Harvest of a Monoclonal Antibody From NS0 Cell Culture: A Case Study
Ying Zhu and Amit Varma

9:10 AM

(511c) Evaluation of a Centrifugation Scale-Down System for Bench-Scale Process Development
Matthew Westoby, Yik Lam, Ryan Haverstock, Carson Fuller and Katie Golson

9:30 AM

(511d) Modeling Buffer Preparation Operations for Downstream Processing
Charles Siletti and Demetri Petrides

9:50 AM

Break

10:00 AM

(511e) Viscosity Reduction through Co-Expression of Nuclease for Improved Clarification
Bangaru Balasundaram, Darren Nesbeth, John Ward, Eli Keshavarz-Moore and Daniel Bracewell

10:20 AM

(511f) Characterization of Rabies Virus Vaccine Inactivation
Veysel Kayser and Bernhardt L. Trout

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division