Session: Protein Engineering I - Therapeutics (2009 Annual Meeting)

Wednesday, November 11, 2009: 8:30 AM

Bayou D (Gaylord Opryland Hotel)

Description:

This session will focus on protein engineering for therapeutic applications with an emphasis on emerging topics and recent successes. Possible areas of interest include, but are not limited to, (1) advances in protein-based therapeutics, (2) proteins for cellular targeting and imaging, (3) proteins involved in disease pathology, and (4) protein-based biomaterials.

Sponsor:

Bioengineering

Chair:

Scott Banta
Email: sb2373@columbia.edu

Co-Chair:

Szu-Wen Wang
Email: wangsw@uci.edu

8:30 AM

(381a) Tumor Idiotype-Based Virus-Like Particle Vaccines for B-Cell Lymphoma
Kedar G. Patel, Patrick P. Ng, Shoshana Levy, Ronald Levy and James R. Swartz

8:50 AM

(381b) Tumor Targeting Fibronectin Domains
Benjamin J. Hackel and K. Dane Wittrup

9:10 AM

(381c) Towards the Rational Design of p53 Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant
Joel L. Kaar, Nicolas Basse, Giovanni Settanni, Andreas C. Joerger, Trevor J. Rutherford and Alan R. Fersht

9:30 AM

(381d) Targeting the Vasculature of Solid Tumors with Enzyme/Prodrug and Methionine-Depletion Therapy
Yahya A. Lazrak, Brent D. Van Rite, Magali Pagnon, Arafat Tfayli, Peter S. McFetridge and Roger G. Harrison

9:50 AM

Break

10:00 AM

(381e) Direct Epitope Mapping of T Cells From Influenza A Virus Genome Using Yeasts Displaying MHC-Peptide Complexes as Artificial Antigen Presenting Cells
Fei Wen, Olga Esteban and Huimin Zhao

10:20 AM

(381f) Design of a Peptide Probe for Rapid and Specific Detection of Amyloid Oligomers
Yang Hu, Chung-sei Kim, Michael Hernandez, Jorge Ghiso, Agueda A. Rostagno and Jin Ryoun Kim

10:40 AM

(381g) Directed Evolution and Structural Characterization of A Simvastatin Synthase
Xinkai Xie, Xue Gao, Inna Pashkov, Micheal Sawaya, Jenal Laidman, Wenjun Zhang, Ralph Cacho, Todd Yeates and Yi Tang

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division