Session: Automatic Control and Qbd (2009 Annual Meeting)

Thursday, November 12, 2009: 8:30 AM

Bayou A (Gaylord Opryland Hotel)

Description:

This session focuses on the use Automatic Process Control in QbD. The use of automatic control can be seen both as a strategy to maintain the process inside an envelope of operation, or as a strategy to extend the envelope of operation. Authors are invited to share their experience in the multiple steps of developing a controller and how the controller was embedded within a QbD exercise and the advantages of doing so

Sponsor:

Topical I: Comprehensive Quality by Design to Develop and Manufacture Pharmaceutical Products

Co-Sponsor(s):

Systems and Process Design (10a), Process Development Division (12), Food, Pharmaceutical & Bioengineering Division (15)

Chair:

Salvador García Muñoz
Email: Salvador.Garcia-Munoz@pfizer.com

Co-Chair:

David R. Vinson
Email: David.Vinson@tufts.edu

8:30 AM

(499a) Controllability Analysis and Identification of Optimal Control-Loop Pairings in a Multiple-Input Multiple-Output Granulation Process
Rohit Ramachandran, Charles D. Immanuel and Frantisek Stepanek

8:55 AM

(499b) Expanding the Acceptance Region for Incoming Materials Via the Usage of a Mid-Course Correction Controller for Wet Granulation
Salvador Garcia-Munoz, Stephanie Brecht and Howard W. Ward II