Tuesday, November 18, 2008: 8:30 AM-11:00 AM
Washington C Room (Loews Philadelphia Hotel)

Topical A: Systems Biology (TA)

#251 - Synthetic Systems Biology (TA001)
Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined systemís behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.
Chair:Christina Smolke
CoChair:Lingchong You
8:30 AMComputational Design of Orthogonal Ribosomes In Bacterial Hosts
Lon Chubiz, Christopher V. Rao
8:51 AMSpatiotemporal Modulation of Biodiversity in a Synthetic Predator-Prey Ecosystem
Hao Song, Meagan Gray, Lingchong You
9:12 AMMultiple Transcription Factor Binding Sites Can Lead to Noise-Induced Bistability In Gene Expression
Tsz-Leung To, Narendra Maheshri
9:33 AMForward Engineering of Synthetic Bio-Logical and Gates
Jonathan R. Tomshine, Kavita Iyer, Jennifer A. Maynard, Yiannis N. Kaznessis
9:54 AMMultiplex Recombineering: Progress toward the Multigenic Insertion of Regulatory Elements and Potential Applications In Metabolic Engineering
Ryan T. Gill, Joseph R. Warner, Lauren B. Andrews
10:15 AMEngineering Microbial Production of Glucaric Acid
Tae Seok Moon, Sang-Hwal Yoon, Kristala L. Jones Prather

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