Monday, November 17, 2008: 12:30 PM-3:00 PM
Room 113-C (Pennsylvania Convention Center)

Bioengineering (15c)

#66 - Advances in Metabolic Engineering and Bioinformatics II (15C22)
Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. Experimental and mathematical techniques that are used to characterize metabolic networks are also included. Bioinformatics tools are critical for the advancement of metabolic engineering and many other fields in biotechnology. Abstracts describing new developments in these topics are sought, and those incorporating both mathematical modeling and experimental aspects are particularly encouraged. Example areas include quantification of metabolic fluxes, inverse metabolic engineering, production of novel products, application of evolutionary techniques, construction of metabolic models from genomic data, incorporation of microarray and proteomic data and mathematical modeling of metabolism. The session is open to papers focused on any type of organism.
Chair:Vassily Hatzimanikatis
CoChair:Nathan D. Price
12:30 PMBiobutanol from Yeast. A Synergistic Genome and Protein Engineering Approach
Nikhil U. Nair, Zengyi Shao, Hua Zhao, Ryan P. Sullivan, Michael McLachlan, Tyler W. Johannes, Huimin Zhao
12:50 PMEffects of Glucose and Insulin Levels on HepG2 Cell Metabolism
Vidya V. Iyer, Charles M. Roth, M.G. Ierapetritou
1:10 PMDistilling the Complexity of Metabolic Chemistry
Christopher Henry, Linda J. Broadbelt, Vassily Hatzimanikatis
1:30 PMCoregulation Analysis of Highly Coexpressed and Non-Coexpressed Genes with a Novel Promoter Similarity Index
Nguyen Tung, Richard Nowakowski, Ioannis P. Androulakis
1:50 PMBreak
2:00 PMImproving Cofactor Availability through Metabolic Engineering for Recombinant Phytochemicals Production
Joseph Chemler, Zachary Fowler, Mattheos Koffas
2:20 PMIdentification of Optimal Measurement Sets for Isotopically Non-Stationary Mfa Experiments
YoungJung Chang, Patrick F. Suthers, Costas D. Maranas
2:40 PMDetermining Metabolic Fluxes Using Experimental Measurements
Jennifer L. Reed, Qiang Hua, Bernhard O. Palsson

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