Tuesday, November 18, 2008: 12:30 PM-3:00 PM
Room 107-B (Pennsylvania Convention Center)

Bioengineering (15c)

#313 - Protein Engineering II: Computational Approaches (15C18)
The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) Protein engineering via directed evolution; (4) Structure- or sequence-based and computational protein engineering and design; (5) Applications of protein engineering.
Chair:Jennifer A. Maynard
CoChair:Lianhong Sun
12:30 PMDe Novo Protein Design of Complement 5a
Ho Ki Fung, Christodoulos A. Floudas
12:50 PMDesign and Characterization of Peptides That Target Transmembrane Helices
Bryan Berger, Hubert Yin, Joanna Slusky, Greg Caputo, Rustem Litvinov, James Lear, Joel Bennett, William DeGrado
1:10 PMHigh-Resolution Homology Modeling of Antibody Fv Regions and Application to Antibody-Antigen Docking
Arvind Sivasubramanian, Aroop Sircar, Sidhartha Chaudhury, Jeffrey J. Gray
1:30 PMOptimal Protein Library Design Using Recombination or Point Mutations Based on Sequence Based Scoring Functions
Robert J. Pantazes, Costas D. Maranas
1:50 PMBreak
2:00 PMAltering Effector Specificity in An Engineered Protein Switch by a Combination of Computational Design and Directed Evolution
Richard A. Heins, Jin Ryoun Kim, Loren L. Looger, Takayuki Soka, Marc Ostermeier
2:20 PMRe-Wiring Protein Structures
Philippa J. Reeder, Jonathan Dordick, Christopher Bystroff
2:40 PMA Rapid, General Platform to Identify Structure/function Relationships of a Viral Protein
James T. Koerber, David V. Schaffer

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