Monday, November 17, 2008: 3:15 PM-5:45 PM
Commonwealth A2 (Loews Philadelphia Hotel)

Pilot Plant Centenary Celebration (TF)

#144 - Data Mining and Modeling of Unit Operations - Sponsored by Group 12b, Pilot Plants (TF003)
Pilot plants typically cover a wider range of parameter space than ever achieved in commercial operations. Data mining to make optimal use of learnings at the pilot phase, and detailed modeling of specific unit operations to obtain accurate and reliable scaleup information, is the subject of this session. Topics include best practices and example studies.
Chair:Praveen K. Sharma
CoChair:Merril Galloway
3:15 PMWelcoming Remarks
3:20 PMData-Mining and Modeling of a Centrifuge
Praveen K. Sharma, Peter Clark, Richard Schild, Jose E. Tabora, Andrew Wilson
3:45 PMThe Design and Scale-up of An API Crystallization: Process Understanding Supported by Modeling to Achieve Consistency
James Wertman, Sonja Sharpe, Christopher Werner
4:10 PMModeling and Implementation of a Mass Transfer Limited Reaction In Kilo and Pilot Plant Settings
Seth Huggins, Ken McRae
4:35 PMAn Example from GSK 's Design for Manufacture Initiative: Use of Dynochem In Conjunction with Lab and Pilot Scale Data to Advance Process Understanding
Hawthorne Graddy, Robert Herrmann, Edward C. Webb, Ravinder Sudini, Dharmesh Bhanushali
5:00 PMPractical Applications of Modeling in Early-Phase API Process Development
Martin Guinn

See more of Topical F: Pilot Plant Centennial Celebration - Sponsored by Group 12b, Pilot Plants

See more of The 2008 Annual Meeting