Monday, November 17, 2008: 8:30 AM-11:00 AM
Franklin 2 (Marriott Philadelphia Downtown)

Bionanotechnology (22b)

#16 - Bionanotechnology for Gene and Drug Delivery I (22B02)
Bionanotechnology uses concepts from chemistry, physics, and molecular biology to identify components and processes for the construction of nanomaterials and nanodevices for health care. This session invites papers that focus on the design and development of nanomaterials and nanodevices for gene and drug delivery. Topics of interest include, but are not limited to: novel methods and compositions to design gene and drug delivery systems at the nanoscale level, and the effects of the sizes of gene and drug delivery systems on gene and drug release kinetics, and pharmacokinetics, cellular uptake, biological transport, and bioefficacy of gene- and drug-carrier complexes.
Chair:Tao L. Lowe
CoChair:Junghae Suh
8:30 AMα5β1-Targeted Stealth Liposomes for Delivery of DNA to Cancer Cells
Alison W. Tisdale, Alice Hsu, R. Scott McIvor, Efrosini Kokkoli
8:50 AMABC Triblock Copolymer Micelleplexes for Potent Gene Silencing and In Vivo Tumor Targeting
Dana J. Gary, Rahul Sharma, You-Yeon Won
9:10 AMRgd-Targeting of PAMAM Dendrimers for Efficient Delivery of siRNA to Malignant Glioblastoma Cells
Carolyn L. Waite, Sarah M. Sparks, Kathryn E. Uhrich, Charles M. Roth
9:30 AMDrug Release Kinetics from Dendritic Nanodevices for Sustained Delivery
Yunus Emre Kurtoglu, Rangaramanujam M. Kannan
9:50 AMDesign of a Multivalent Binding Platform for Enhanced Non-Viral Gene Transfer to αvβ3 Expressing Cells
Quinn Ng, Tatiana Segura
10:10 AMPreparation and Stabilization of Biodegradable Cationic Polyelectrolyte Complexes for Targeted Drug Delivery
Sameer Dalvi, Anagha Bhakay, Rajesh Davé, Habibe Karacay
10:30 AMProdrug Conjugates to Improve the Delivery Capacity of Nanoparticles for Protein Therapeutics
Marian E. Gindy, Robert K. Prudhomme

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