| Wednesday, November 19, 2008: 3:15 PM-5:45 PM | |||
| Washington A Room (Loews Philadelphia Hotel) | |||
Process Research and Innovation (12a) | |||
| #521 - Applications of Chemometrics for Process Development (12A01) | |||
| Innovations in Process Development are empowered by using Chemometrics techniques to derive useful information from complex data systems. A wide range of chemometrics applications is encompassed in this session, including increased process understanding through optimization of experimental parameters, design of experiments, calibration, signal processing and enhancement of PAT development. | |||
| Chair: | James Marek | ||
| CoChair: | Jean W. Tom | ||
| 3:15 PM | Welcoming Remarks | ||
| 3:20 PM | 521a | Introduction to Chemometrics -- Design of Experiments and Principal Component Analysis Dongsheng Bu, Andrew Chu | |
| 3:45 PM | 521b | Data Exploration Analysis In Process Development: Application to API Characterization Jose E. Tabora, Jessica Defreese, Prashant Deshpande, Jean Tom | |
| 4:10 PM | 521c | Scale-up a Complex Pharmaceutical Batch Process Using Mid-IR: The Role of Simple Peak Height Profiling, Partial Least Squares (PLS) Modeling and Dynamic Principal Component Analysis (PCA) Shan Lin, James Marek, Samrat Mukherjee | |
| 4:35 PM | 521d | Application of Chemometrics in Process Monitoring of Synthesizing Preferred Isomer Dongsheng Bu, Andrew Chu | |
| 5:00 PM | 521e | Utilization of Single Crystal X-Ray Studies of Process Relevant Pharmaceutical Crystal Forms to Support Qbd John D. DiMarco, Michael A. Galella, Raymond P. Scaringe, Carolyn J. Pommier, Jack Z. Gougoutas | |
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See more of The 2008 Annual Meeting