| Monday, November 17, 2008: 3:15 PM-5:45 PM | |||
| Room 204-C (Pennsylvania Convention Center) | |||
Topical 5: Green Engineering and Sustainability in the Pharmaceutical Industry (T5) | |||
| #134 - Batch to Continuous Pharmaceutical Processing Challenges (T5007) | |||
| For most companies in the pharmaceutical industry, converting a batch API process into continuous process is likely to go beyond being a technical challenge to the development chemists and engineers. Supporting groups in regulatory, EHS and Quality roles will also be impacted. In this session we want to identify and explore the big challenges facing the development of continuous processes and the conversion of batch to continuous processes. | |||
| Chair: | Daniel R. Pilipauskas | ||
| CoChair: | Fernando J. Muzzio | ||
| CoSponsor(s): | Pharmaceuticals (15b) | ||
| 3:15 PM | Introductory Remarks | ||
| 3:25 PM | 134a | Continuous Processing in Pharmaceutical Process Development Chenchi Wang, Thomas LaPorte | |
| 3:45 PM | 134b | Development of Continuous Flow Processes for Pharmaceutical Manufacturing Jerry S. Salan | |
| 4:05 PM | 134c | Assessing the Effectiveness of a Spinning Tube-In-Tube Reactor James Ciszewski, Michael Gonzalez | |
| 4:25 PM | 134d | Removing Palladium from Reaction Mixtures by Fixed Bed Adsorption Brian G. Lefebvre, Caitlin A. Boyd, Sonia M. Berberena, Laura E. Kuczynski, Pamela L. Kubinski, Megerle L. Scherholz, Dr. Stephanie Farrell, Robert P. Hesketh, Michael J. Girgis | |
| 4:45 PM | 134e | Separation of Fine Chemical Species by Means of Continuous Chromatography: The Simulated Moving Bed Technology Pedro Sá Gomes, Michal Zabka, Viviana Silva, Alírio E. Rodrigues | |
| 5:05 PM | 134f | Possibility of Separating Enantiomeric Compounds Continuously with Supercritical CO2 and Chiral Ionic Liquids Hiroshi Machida, Wataru Endo, Ryosuke Taguchi, Masaru Watanabe, Yoshiyuki Sato, Richard L. Smith | |
| 5:25 PM | 134g | Effects of Rotation Rate, Mixing Angle, and Cohesion In Two Continuous Powder Mixers – a Statistical Approach Patricia M. Portillo, Aditya U. Vanarase, M.G. Ierapetritou, Fernando J. Muzzio | |
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