Tuesday, November 18, 2008: 8:30 AM-11:00 AM
Room 106-A (Pennsylvania Convention Center)

Topical 5: Green Engineering and Sustainability in the Pharmaceutical Industry (T5)

#223 - Green Reactions In the Pharmaceutical Industry (T5004)
This session will provide a forum for the discussion of green reactions used in the pharmaceutical industry from research to manufacturing. Papers discussing recent advances, fundamentals, and industrial applications are welcome at the session. Topics include green reaction pathways, increasing the efficiency of reactions, using enzyme, biocatalysts, etc as well as emerging trends and future directions in green reactions. Modeling and experimental investigations as well as case studies showing improvements to minimize environmental impacts are welcome.
Chair:Sanjeev Katti
CoChair:Amit Mehrotra
CoSponsor(s):Pharmaceuticals (15b)
8:30 AMGreen Chemistry in the Redesign of the Celecoxib Manufacturing Process
Leo J. Letendre, Cynthia Snoddy, George H. Klemm, William McGhee
8:55 AMAsymmetric Bioreduction of Nitro-Substituted Compounds with Three Enoate Reductases
Yanto Yanto, Mélanie Hall, Andreas S. Bommarius
9:20 AMWater Tolerant Lewis Acid Catalysis of Organic Reactions In High Temperature Water
Natalie A. Rebacz, Phillip E. Savage
9:45 AMCombi-Clea for Reactions in Continuous Flow Supercritical CO2
Betti Kondor, Juan García-Serna, Neil R. Thomas, Martyn Poliakoff, María José Cocero
10:10 AMKinetics of Hydroformylation of Higher Olefins Using Rhodium-Phosphite Catalyst in a Thermomorphic Solvent System
Binay K. Dutta, Maizatul Shima Shahrun, Hilmi Mukhtar, Suzana Yusuf

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