Monday, November 17, 2008: 8:30 AM-11:00 AM
Room 204-C (Pennsylvania Convention Center)

Topical 5: Green Engineering and Sustainability in the Pharmaceutical Industry (T5)

#13 - Benign / Safer Solvents In Pharmaceutical Processing (T5002)
This session will provides an opportunity to discuss the development and use of benign / safer solvents in the pharmaceutical and specialty chemical industry. Papers discussing recent advances, fundamentals, and industrial applications are welcome at the session. Topics include current practices in the use of benign / safer solvents as well as emerging trends and future directions. Case studies assessing the environmental improvements resulting from using greener solvents and associated processes are welcome.
Chair:David J. C. Constable
CoChair:Ann Lee-Jeffs
CoSponsor(s):Pharmaceuticals (15b)
8:30 AM13aBusiness Case: Pharmaceutical Sustainability
Ann Lee-Jeffs, John Leazer
8:50 AM13bModel Based Solvent Selection with NRTL-SAC Including Use of Chromatographic Retention Times as Model Input
Alexander J. Marchut, Olav Lyngberg, Chau-Chyun Chen
9:10 AM13cPiperylene Sulfone: Fully Recyclable Diprotic Apolar Solvent for Benign Pharmaceutical Processes
Charles A. Eckert, Charles L LIotta, Douglas P. Kjell
9:30 AM13dSelf-Condensation of Acetophenone to Dypnone: Synergism of Microwave and Solid Acid Catalysts
Ganapati D. Yadav, Ginish George
9:50 AM13eHomogeneous Catalysis Coupled with Benign Separation In Polyethylene Glycol-Organic-Carbon Dioxide Tunable Solvent Systems
Vittoria M. Blasucci, Megan Donaldson, Charles A. Eckert, Charles L. Liotta
10:10 AM13fCollaboration to Deliver a Solvent Selection Guide for the Pharmaceutical Industry
Caireen R. Hargreaves
10:30 AM13gSolvents In Organic Synthesis: Replacement and Multi-Step Reaction Systems
Rafiqul Gani, Concepcion Jimenez-Gonzalez, David Constable, Muhammad Shafique Bashir

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