Wednesday, November 19, 2008: 8:30 AM-11:00 AM
Room 107-B (Pennsylvania Convention Center)

Bioengineering (15c)

#392 - Advances In Protein Expression and Post-Translational Modification (15C06)
Increasing demand for recombinant proteins has focused research on techniques for improving protein expression and controlling post-translational processing. We invite papers on all aspects of protein expression including novel cell systems, expression vectors, and culture conditions. Submissions dealing with post-translational processing including glycosylation, editing and secretion are also invited. Papers may deal with any cell type including bacteria, yeast, mammalian, insect and plant cell cultures.
Chair:Satish J. Parulekar
CoChair:Sobin Kim
8:30 AMDevelopment of the Photoheterotroph Rhodobacter for Functional Membrane Protein Expression
Brandon S. Curtis, Philip D. Laible, Deborah K. Hanson, Wayne Curtis
8:50 AMEngineering Saccharomyces Cerevisiae for the Heterologous Expression of Mammalian G-Protein Coupled Receptors
Michelle O'Malley, J. Dominic Mancini, Carissa L. Young, David Raden, Anne Skaja Robinson
9:10 AMEnhancing Protein Secretion In E. Coli by Codon Engineering
Prateek Gupta, Kelvin H. Lee
9:30 AMExpression and Reconstitution of Fungal Polyketide Synthases
Suzanne M. Ma, Jin Wook Choi, Yi Tang, Nancy A. Da Silva
9:50 AMBreak
10:00 AMInvestigating the Status of Oxidative Protein Folding in Escherichia Coli Missing Components of the Thiol-Redox Pathways
Karthik Veeravalli, Melinda Faulkner, Constantine Chrysostomou, Jon Beckwith, George Georgiou
10:20 AMIncomplete Quality Control of Yeast-Secreted Multidomain Proteins
Andrew W. Nields, Eric T. Boder
10:40 AMTriple Light Chain Antibodies in Thiomabs
Natalia Gomez, Abigail Vinson, Jun Ouyang, Inn Yuk

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