Monday, November 17, 2008: 8:30 AM-11:00 AM
Room 113-C (Pennsylvania Convention Center)

Bioengineering (15c)

#12 - Advances In Metabolic Engineering and Bioinformatics I (15C05)
Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. Experimental and mathematical techniques that are used to characterize metabolic networks are also included. Bioinformatics tools are critical for the advancement of metabolic engineering and many other fields in biotechnology. Abstracts describing new developments in these topics are sought, and those incorporating both mathematical modeling and experimental aspects are particularly encouraged. Example areas include quantification of metabolic fluxes, inverse metabolic engineering, production of novel products, application of evolutionary techniques, construction of metabolic models from genomic data, incorporation of microarray and proteomic data and mathematical modeling of metabolism. The session is open to papers focused on any type of organism.
Chair:Xiaoxia (Nina) Lin
CoChair:Kenneth F. Reardon
8:30 AMEnsemble Modeling - a Novel Tool for Strain Design
Matthew L. Rizk, Linh M. Tran, James C. Liao
8:50 AMGenome Sequencing Reveals Novel Features of Metabolism In Agrobacterium Sp
Anne Ruffing, Marlene Castro, Wei-Shou Hu, Rachel Ruizhen Chen
9:10 AMMicrofluidic Droplets as Nanobioreactors for Screening Metabolic Engineering Libraries
Benjamin L. Wang, Hang Zhou, David A. Weitz, Gregory N. Stephanopoulos
9:30 AMDetermining the Molecular Mechanisms of Adaptive Evolution In Yeast
Katy Kao, Gavin Sherlock
9:50 AMBreak
10:00 AMExhaustive Identification of All Engineering Interventions Leading to Targeted Overproductions
Sridhar Ranganathan, Patrick F. Suthers, Costas D. Maranas
10:20 AMDevelopment of Efficient Organisms Using a Combination of Rational Strain Design and Metabolic Evolution
Pornkamol Unrean, Cong Trinh, Friedrich Srienc
10:40 AMIsotopically Nonstationary 13C Flux Analysis of Synechocystis Photoautotrophic Metabolism
Jamey D. Young, Avantika A. Shastri, Gregory Stephanopoulos, John A. Morgan

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