Friday, November 21, 2008: 8:00 AM-10:30 AM
307-A (Pennsylvania Convention Center)

Engineering Fundamentals in Life Science (15d)

#729 - Engineering Biomolecules (15D15)
This session invites contributions on novel methods for engineering biomolecules and the applications of these in therapeutics, diagnostics, sensors, and other engineering applications. Fundamental experimental and computational studies on the structure and structure-function properties of engineered biomolecules are also welcome.
Chair:S. Patrick Walton
CoChair:Kaushal Rege
8:00 AMPetrobactin Biosynthesis: A Target for Antibiotics and a Platform for Producing Specialty Chemicals
Brian Pfleger, David Sherman, Tyler Nusca, Jaime Scaglione, Jung-Yeop Lee
8:20 AMA Polyketide Macrolactone Synthase from the Filamentous Fungus Gibberella Zeae
Hui Zhou, Yi Tang
8:40 AMStudying the Structural Properties of Nesprin-1α By Using Engineered Protein Fragments
Zhixia Zhong, Siwei Chang, Katherine Wilson, Kris Noel Dahl
9:00 AMCharacterization and Engineering of Peptide Binding to Class II Mhc by Yeast Co-Expression
Wei Jiang, Eric T. Boder
9:20 AMBreak
9:30 AMPrediction of siRNA Functionality Using Sequence and Thermodynamic Properties
Charles M. Roth, Pratik Sheth, Anik Jain, Vinit Shah, Stanley M. Dunn
9:50 AMEngineering Vectors for Dual Gene Expression from Independent Promoters for High Throughput Studies
Jun Tian, Stelios T. Andreadis
10:10 AMMolecular Barcode-Labeled Aptamers for Biosensor Applications
Shengnan Xie, S. Patrick Walton

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