Tuesday, November 18, 2008: 12:30 PM-3:00 PM
Room 109-B (Pennsylvania Convention Center)

Pharmaceuticals (15b)

#261 - Advances in API Process Development (15B02)
The application of PATs in process development laboratories has expedited development timelines, while providing increased process understanding. Traditional engineering approaches like kinetic regression and mass transfer analysis using PAT data and subsequent process simulation will be the focus of this session. Authors are encouraged to submit papers discussing novel techniques aimed at solving process problems and interesting API case studies.
Chair:Partha Mudipalli
CoChair:Jean W. Tom
12:30 PMControl of API Powder Properties Via Cake Washing Protocol and Agitated Drying
Jessica L. Defreese, Derek Berglund, Prashant P. Deshpande, Mauricio Futran
12:50 PMFlocculated Amorphous Nanoparticles for Enhanced Bioavailability of Poorly-Water Soluble Drugs: In-Vitro and in-Vivo Studies
Maria Andrea Miller, Michal E. Matteucci, Robert O. Williams III, Keith P. Johnston
1:20 PMPreserving API Hemihydrate during Vacuum Drying
Erwin Irdam
1:40 PMUse of In-Line FTIR for the Kinetic Study of the Reaction and Degradation of Propylene Oxide In the Synthesis of a Pharmaceutical Intermediate
Thomas Laporte, Zhongmin Xu, Fernando Quiroz, Lori Spangler, Chiajen Lai, Jean Tom
2:00 PMControl of Particle Sizes In An API Crystallization Process Via Thermal Cycling
Yao-En (David) Li, Shaila Perez, Warrant Holmes, Yanhui Hu, Gerrie Liaw, Yubo Yang
2:20 PMPoly(Ethylene) Glycol-Drug Eutectic Compositions: Complex Morphologies and Crystallization Kinetics
Phong Huynh, Paul Takhistov

See more of Food, Pharmaceutical & Bioengineering Division

See more of The 2008 Annual Meeting