Thursday, November 8, 2007: 12:30 PM-3:00 PM
Room 254 C (Salt Palace Convention Center)

Engineering Fundamentals in Life Science (15e)

#577 - Cardiovascular Disease and Cancer I (15E14)
This session will highlight engineering approaches to understand problems in cancer, cardiovascular and other diseases and to develop advanced therapeutic strategies. Emphasis will be on studies of transport, heat transfer, kinetics, and cell and tissue mechanics specifically relevant to the areas of tumor biology, metastasis, and vascular pathophysiology. Topics of interest include angiogenesis, atherosclerosis, cancer cell adhesion and migration, cancer cell signaling and intracellular metabolism. Of specific interest are studies involving novel therapeutic strategies, including molecular/cell-based therapies, with aims to inhibit cancer progression and metastasis and to regenerate new functional blood vessels.
Chair:Hyun Joon Kong
CoChair:Cynthia Reinhart-King
12:30 PMStructure-Function Relationships in Cardiac Myocytes*
Kit Parker
12:50 PMQuantitative Analysis of the Effects of Vegf-Signaling on Bone Marrow-Derived Cell Recruitment and Accumulation in Lung Metastases
Michelle R. Dawson, Dan G. Duda, Rakesh K. Jain
1:10 PMMolecular And Biophysical Regulators Of Lymphatic Transport
Joseph M. Rutkowki, Carolyn Yong, Melody A. Swartz
1:30 PMDiscovery of Specific Tumor Targeting Peptides Using Fluorescent Bacterial Display Libraries
Karen Y. Dane, Patrick S. Daugherty
1:50 PMBreak
2:00 PMDifferential In Vitro Cytotoxicity Of Doxorubicin And 5-Fluorouracil To Cancer And Normal Human Mammary Epithelial Cells
Anand K. Ramasubramanian, Douglas S. Clark
2:20 PMMultilayer Microfluidics For Studying Thrombosis
Keith B. Neeves, Scott L. Diamond
2:40 PMFluid Shear Induces Conformation Change In Human Blood Protein Von Willebrand Factor Solution Structure
Indrajeet Singh, Lionel Porcar, Sriram Neelamegham

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