Tuesday, November 6, 2007: 12:30 PM-3:00 PM
Room 250 C (Salt Palace Convention Center)

Pharmaceuticals (15b)

#214 - Advances in Protein Structure, Function and Stability I (15B08)
Advances in Protein Structure, Function, and Stability: We invite submissions in the areas of experimental, theoretical, and computational approaches to prediction, design, and/or optimization of protein structure, stability, and function. Studies may include structural analysis and engineering of proteins, creation or optimization of function, conformational analysis, analysis of thermal stability, mechanism of protein folding and misfolding, modes of protein degradation via physical and chemical routes, and other issues involving (over)expression, purification, and final biopharmaceutical product formulation. Reports of studies both in laboratory and processing settings relevant to all biotechnology products are welcome. Investigations of molecular pathways and mechanisms that provide insights into human diseases and potential treatments are of particular interest to this session.
Chair:Sheldon Park
CoChair:Peter M. Tessier
CoSponsor(s):Bioengineering (15c)
12:30 PMBiophysical Characterization Of The Human Adenosine A2a G-Protein Coupled Receptor Expressed From Saccharomyces Cerevisiae
Michelle O'Malley, Tzvetana Lazarova, Anne Skaja Robinson
12:50 PMComputational Predictions For Sequence Specificity Of Mrna Binding Proteins
M. A. Ovacik, A. Jain, Anna Knapinska, G. Brewer, I.P. Androulakis
1:10 PMMicrofluidic Device For Combinatorial Chemistry
Sowmya Kondapalli, David A. Putnam, Brian J. Kirby
1:30 PMEvolution Of [Fefe] Hydrogenases For Biological Hydrogen Production
James A. Stapleton, James R. Swartz
1:50 PMBreak
2:00 PMPrediction of Protein Solubility in Escherichia Coli Using Discriminant Analysis, Logistic Regression, and Artificial Neural Network Models
Reese Lennarson, Rex Richard, Armando Diaz, Miguel J. Bagajewicz, Roger Harrison
2:20 PMThe Unfolding Behavior And Operational Stability Of Tem-1 Beta-Lactamase
Thomas A. Rogers, Andreas S. Bommarius
2:40 PMProtein Engineering Of Extremophilic Chaperones To Build Controllable Structures At The Nanoscale
Timothy Whitehead, Douglas S. Clark

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