Membranes are used throughout the manufacturing process of monoclonal antibodies. This presentation in the membrane tutorial section will highlight some recent developments in which new membranes are explored to improve process economics and address regulatory demands.

First, high performance tangential flow filtration will be discussed as an example of how a standard method of seperation can be enhanced by membrane modification.

Secondly, the use of membranes as chromatography media will be discussed. Rather than relying on size exclusion as is typically done for membrane operations, the convective flow through pores is used to more effectively utilize all the surface area of membranes. Some new devlopments will be highlighted here.