Monday, November 13, 2006: 3:15 PM-5:45 PM
Franciscan B (Hilton San Francisco)
#116 - Agglomeration and Granulation Processes II (03A06)
We plan a session about all aspects of particles size increase i.e., formation of larger granules from fine particles with or without the use of a binder. This will cover wet-and melt-granulation, fluid bed granulation and coating and compaction under pressure. Papers are requested on both theoretical, computer modeling and experimental research performed on the above systems.
Chair:Karen P. Hapgood
CoChair:Paul Mort
3:15 PMBinder Selection in Pharmaceutical Granulation: Wetting, Spreading, Stickiness and Strength
Stefaan J. R. Simons, Rob Ward, Shaun Fitzpatrick, Cristina Jimenez
3:35 PMGranulation of Hydrophobic Powders Via Solid Spreading Nucleation
Karen P. Hapgood
3:55 PMThe Microscopic Study of Granulation Mechanisms and Their Effect on the Non-Uniformity of Granule Properties
Phung K. Le, Paul Avontuur, Michael J. Hounslow, Agba D. Salman
4:15 PMTop-Spray Fluidised Bed Coating: Scale-up Using Response Surface Methodology
Peter Dybdahl Hede, Poul Bach, Anker D. Jensen
4:35 PMStudy of the Mechanisms during Drying of a Pharmaceutical Fluid Bed Granulation: Correlation of Residual Water Content with the Chemical Stability of the Formulation
Padma J. Narayan, Robert Batten, Bridget Larson, Meegan LeMott, Hong Ren Wang, Stephanie Tokarczyk, Ruby Burke, Marco Verwijs, Di Chen, Chris Galli
4:55 PMEffect of Initial Particle Size and Initial Distribution Shape (Unimodal and Bimodal) on the Growth Kinetics and Mechanism of Wet Granulation in a Laboratory-Scale High Shear Mixer by Means of Image Processing and Analysis
Alvaro Realpe, Carlos Velázquez

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