Thursday, November 16, 2006: 8:30 AM-11:00 AM
Yosemite B (Hilton San Francisco)
#484 - Advances in Metabolic Engineering and Bioinformatics (II) (15C01)
This session will focus on Metabolic Engineering as a molecular-systems approach to the understanding and utilization of metabolic processes. The goal of the session is to discuss very recent advances in modeling and experimental approaches necessary to understand the integration and control of genetic, catalytic, and other biochemical events that govern cellular metabolism. Topics of interest include: reconstruction of metabolic as well as gene regulatory networks; control analysis; genomic, proteomic and/or metabolomic analysis; optimization; and heterologous pathways. We invite papers on the development and application of these techniques to cells derived from plant, insect, and animal tissues.
Chair:Kyongbum Lee
CoChair:Christina Chan
8:30 AMUnderstanding Cofactor Partitioning in Xylitol-Producing Escherichia Coli Expressing Xylose Reductase
Jonathan W. Chin, Costas D. Maranas, Patrick C. Cirino
8:50 AMMetabolic Control Analysis Provides Insights into Strategies for Improving Ethanol Production from Recombinant Xylose-Utilizing Saccharomyces Cerevisiae
Liqing Wang, Vassily Hatzimanikatis
9:10 AMSimultaneous Estimation of Reaction Fluxes and Metabolite Levels Using Instationary 13C Metabolic Flux Analysis
Jamey D. Young, Jason L. Walther, Maciek R. Antoniewicz, Gregory N. Stephanopoulos
9:30 AMTotal Microbial Synthesis of Benzylisoquinoline Alkaloids in Saccharomyces Cerevisiae
Kristy M. Hawkins, Christina Smolke
9:50 AMBreak
10:00 AMForward Engineering of a S. Coelicolor Actinorhodin Overproducer Using Transposon Mutagenesis
Elizabeth Widenbrant, Camilla M. Kao
10:20 AMEngineering of Organic Acid Tolerance Genes in E. Coli for Biorefinery Applications
Tanya Warnecke, Michael D. Lynch, Nicholas R. Sandoval, Ryan T. Gill
10:40 AMBiosynthesis of Fosfomycin
Zengyi Shao, Ryan Woodyer, Huimin Zhao

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