Monday, November 13, 2006: 3:15 PM-5:45 PM
Continental 4 (Hilton San Francisco)
#128 - Engineering Fundamentals of Drug Delivery (TG001)
The purpose of this session will be to examine recent advanced on the fundamentals of drug delivery including mathematical modelling of controlled release behavior, advanced protein/drug diffusion theories, anomalous drug transport behavior, theories of drug absorption and mathematic sof protein transport across the intestinal wall.
Chair:Allan S. Hoffman
CoChair:Kakuji Tojo
3:15 PMImproving the Oral Delivery of Macromolecules through the Study of Permeation Enhancers
Kathryn A. Whitehead, Samir Mitragotri
3:40 PMEffect of Molecular Weight of Penetrants on Iontophoretic Transdermal Delivery in Vitro
Takamitsu Miyagi, Tomohiro Hikima, Kakuji Tojo
4:00 PMSkin Enzymes Distribution in Transdermal Drug Delivery
Tomohiro Hikima, Howard I. Maibach, Kakuji Tojo
4:20 PMFinite Element Model of Controlled Release Via the Degradation and Erosion of a Polymer Matrix
Sam N. Rothstein, William Federspiel, Steven Little
4:40 PMChemotherapy with Drug-Free Hybrid Liposomes
Yoko Matsumoto, Hideaki Ichihara, Ryuichi Ueoka
5:00 PMIn Vivo Evaluation of Skin Permeability of Drugs after Applying Adhesive Transdermal Patch
Kakuji Tojo
5:25 PMPhysiological Modeling of Gastrointestinal Tract for Predicting the Effect of Cyclodextrin on Bioavailability of Neutral Compounds
Saloni Bhardwaj, Ece D. Gamsiz, Rebecca L. Carrier

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