Wednesday, November 15, 2006: 8:30 AM-11:00 AM
Continental 9 (Hilton San Francisco)
#329 - Advances in Metabolic Engineering and Bioinformatics (I) (15C15)
This session will focus on Metabolic Engineering as a molecular-systems approach to the understanding and utilization of metabolic processes. The goal of the session is to discuss very recent advances in modeling and experimental approaches necessary to understand the integration and control of genetic, catalytic, and other biochemical events that govern cellular metabolism. Topics of interest include: reconstruction of metabolic as well as gene regulatory networks; control analysis; genomic, proteomic and/or metabolomic analysis; optimization; and heterologous pathways. We invite papers on the development and application of these techniques to cells derived from plant, insect, and animal tissues.
Chair:Kyongbum Lee
CoChair:Christina Chan
8:30 AMElementary Metabolite Units (Emu): a Novel Framework for Modeling Isotopic Tracer Distributions and Determining Metabolic Fluxes
Maciek R. Antoniewicz, Jose Aleman, Joanne K Kelleher, Gregory N. Stephanopoulos
8:50 AMGenome-Scale Metabolic Systems Design by Flux Transition Theory
Matthew L. Rizk, James C. Liao
9:10 AMReconstitute Biosynthesis of Tetracycline Intermediates
Wenjun Zhang, Yi Tang
9:30 AMTranscriptomic Studies of an Amorphadiene Producing E. Coli Strain in an Acka/Pta/Poxb Deletion Background
Robert H. Dahl II, Yisheng Kang, Jay D. Keasling
9:50 AMBreak
10:00 AMCharacterization of Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Production in Escherichia Coli
Matthew S. Wong, Thomas B. Causey, Nikos Mantzaris, George N. Bennett, Ka-Yiu San
10:20 AMMetabolic Engineering of E. Coli for Alpha-Gal Epitope Synthesis
Zichao Mao, Anne Ruffing, Rachel Ruizhen Chen
10:40 AMNatural and Unnatural Flavonoid Biosynthesis and Their Insulinotropic Properties in Pancreatic Beta Cells
Lye T. Lock, Effendi Leonard, Yajun Yan, Joseph Chemler, Manolis S. Tzanakakis, Mattheos Koffas

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