Wednesday, November 15, 2006: 8:30 AM-11:00 AM
Yosemite A (Hilton San Francisco)
#336 - Cardiovascular and Cancer (I) (15D06)
This session will highlight engineering approaches to problems in cancer, cardiovascular and other diseases. Emphasis will be on studies of transport, cell and tissue mechanics, heat transfer, and kinetics applied specifically to the areas of tumor biology, metastasis, and the circulation. Topics may span length-scales from molecular to organismal physiology, involving computational and/or experimental methods. Sample topics include: - angiogenesis - atherosclerosis - cancer cell adhesion and migration - cancer cell signaling - intracellular metabolism - diabetes - gene therapies novel therapeutic strategies - ischemia / reperfusion injury - models of tumor development - sickle cell disease - thrombosis/fibrinolysis - tumor pharmacokinetics and drug delivery.
Chair:Neil S. Forbes
CoChair:Edgar O'Rear III
8:30 AMModeling Delivery of Supplemental Nitric Oxide in Resistance Vessels
Daniel R. Hyduke, James C. Liao
8:50 AMA Novel, Quantifiable Three-Dimensional Model of Melanoma Invasion
Cyrus M. Ghajar, Katherine S. Blevins, Vinod A. Suresh, Christopher B. Raub, Steven C. George, Andrew J. Putnam
9:10 AMParsing the Crosstalk between Prominent Oncogenic Signaling Pathways
Nicholas A. Graham, Anand R. Asthagiri
9:30 AMMitochondria Depolarizing Peptides Sensitize Prostate Cancer Cells to Death Receptor Mediated Apoptosis
Kaushal Rege, Martin L. Yarmush
9:50 AMBreak
10:00 AMFibrin-Cd44v Binding Interferes with Platelet-Colon Carcinoma Cell Adhesion under High Shear Conditions
Christina S. Alves, Susan N. Thomas, Parag Pawar, Konstantinos Konstantopoulos
10:20 AMUltrasound-Enhanced Chemotherapy and Gene Delivery for Gliosarcoma Cells
Vladimir G. Zarnitsyn, Pavel Kamaev, Mark R. Prausnitz
10:40 AMTnf-a Based Accentuation of Cryoinjury for the Treatment of Prostate Cancer-Dose, Delivery and Response
Raghav Goel, David Swanlund, James Coad, Guilio Paciotti, John Bischof

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