Thursday, November 16, 2006: 12:30 PM-3:00 PM
Yosemite A (Hilton San Francisco)
#543 - Drug Delivery (I) (15D05)
This session highlights recent research efforts in the broad area of design, characterization (in vitro and in vivo), and development of drug delivery systems with multi-functional properties for targeted and sustained drug delivery. Topics of interest include, but are not limited to: Effects of chemical structure and/or physical properties of drug delivery systems on loading efficiency and release kinetics; functionalizing drug carriers with moieties for specific targeting; blood circulation time and biodistribution of drug-carrier complexes after systemic injection; in vitro and in vivo studies of cellular uptake.
Chair:Efrosini Kokkoli
CoChair:Stavroula Sofou
12:30 PM543aDesign of Targeted Nanocarriers for Optimal Drug Delivery to Stressed Endothelium: a Multiscale Modeling Approach
Joshua Weinstein, Neeraj Agarwal, Ravi Radhakrishnan
12:50 PM543bComparative Analysis of the Uptake and Intracellular Fate of Nanoparticles in Different Epithelial Cell Types
Malgorzata S. Cartiera, K. M. Johnson, V. Rajendran, M. J. Caplan, W. Mark Saltzman
1:10 PM543cEfficient Sirna Delivery with Acetylated Polyethylenimine
Lily Wong, Daniel W. Pack
1:30 PM543dBiodegradable Spray Dried Microspheres and Discs Delivering Paclitaxel and Etanidazole for the Treatment of Giloma: an in Vivo Subcutaneous Study
Benjamin Y. S. Ong, Pavan Kumar Naraharisetti, Jingwei Xie, Chi-Hwa Wang, Nick Sahinidis
1:50 PM Break
2:00 PM543eCoated Microneedles for Transdermal Drug Delivery
Harvinder S. Gill, Mark R. Prausnitz
2:20 PM543fA Biodegradable Fiber for Controlled Delivery of Therapeutics to the Eye
Brendan C. Mack, Kenneth W. Wright, Mark E. Davis
2:40 PM543gDrug Elimination Kinetics in the Eye after Subconjunctival Delivery
Stephanie H. Kim, Robert J. Lutz, Karl G. Csaky, Craig J. Galban, Nam Sun Wang

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