Monday, November 13, 2006: 12:30 PM-3:00 PM
Yosemite A (Hilton San Francisco)
#63 - BioMEMS and Microfluidics: Biomedical Diagnostics (T3005)
Medical diagnostic kits encompass a wide variety of portable analytical devices used to monitor and screen for medical conditions. They are rapidly being developed for use on a single-test basis and show promise as indispensable tools for clinical research, medical laboratories, and at home self-testing. The terms “microdevice”, “microchip”, “lab-on-a-chip” and “micro-electromechanical systems” all refer to small, versatile, inexpensive, rapid-response devices that may be engineered for biomedical applications. Research in the areas of sample introduction, preparation, electrokinetic transport of biofluids, development of quantitative detection sensors, and the incorporation of genomic and proteomic biomarkers are needed to further the advancement of biomedical microdevices. Novel microanalytical tools are welcome, specifically those impacting applications such as genetic predisposition testing, rapid diagnosis of the presence of a particular disease or disorder, or those monitoring the efficacy of drug therapies. The goals of this session are to bring together researchers from academia, research labs, and industry to exchange ideas with the potential to revolutionize medical diagnostics. In particular, this session seeks contributions in the field of biomedical microdevices on either the cellular or subcellular level. Subjects of interest include cellular analysis in microdevices; development and fabrication of innovative devices; novel biofluid separators; advances in microanalytical systems; electrokinetics; dielectrophoresis; advances in chemical, electrochemical, and optical in-line sensor technology; and novel low concentration detection in capillary electrophoresis systems. Original contributions to BioMEMS and biological microfluidics are also encouraged.
Chair:Joseph J. Biernacki
CoChair:Bruce Gale
12:30 PM63aA Continuous Microfluidic Blood/Plasma Separation Unit with Electrokinetic Stirring and Cross-Flow
Shramik Sengupta, Ping Wang, Zachary R. Gagnon, Hsueh-Chia Chang
12:55 PM63bA Fully Automated Nanoliter Viscometer for Analyzing Newtonian and Non-Newtonian Body Fluids and Polymeric Liquids
Nimisha Srivastava, Mark A. Burns
1:20 PM63cA Novel Application of Isotachophoresis to Enhance Immunodiagnostic Assays on a Microchip
Charles Park, Tomohisa Kawabata, Irina Kazakova, Chen Li, Rajiv Bharadwaj, Shinji Satomura
1:45 PM63dPurification of Genomic DNA from Whole Cell Lysates Using Photoactivated Polycarbonate Microfluidic Devices
Malgorzata A. Witek, Shawn D. Llopis, Robin L. McCarley, Steven A. Soper
2:10 PM63eDelivery of Molecules and DNA into Mammalian Cells by Electroporation on a Microfluidic Device
Hsiang-Yu Wang, Nashley Mascarenhas, Shaunak A. Kothari, Chang Lu
2:35 PM63fOn-Chip Electrochemistry Based Real Time Polymerase Chain Reaction
Stephen S. W. Yeung, Thomas Ming-Hung Lee, I.-Ming Hsing

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