Thursday, November 16, 2006: 12:30 PM-3:00 PM
Yosemite B (Hilton San Francisco)
#566 - Systems Biotechnology (15C05)
Systems biotechnology involves understanding the control and cellular dynamics of multiple genes/proteins/small molecules. Typically, a systems biology study involves global measurements on changes in gene, protein or metabolite concentrations in response to environmental or genetic perturbation. The forefront of this research area combines several of these techniques with mathematical modeling to uncover the features leading to phenotypes such as sensitivity or robustness. Possible topics include analysis of intracellular signal transduction, metabolic pathways, cell cycle, circadian rhythms, quorum sensing. Biological systems from single cell microbes to mammalian tissues will be considered.
Chair:John A. Morgan
12:30 PMSystematic Investigation of E. Coli Ai-2 Quorum Sensing Circuit Reveals Alternative Synthesis Pathways
Jun Li, Liang Wang, Yoshifumi Hashimoto, Chenyu Tsao, Thomas K. Wood, William E. Bentley
12:50 PMExploiting Transcriptional Patterns of Antibiotic Activity for Treatment Optimization and Development
Zhigang Zhang, Friedrich Srienc, Arkady Khodursky
1:10 PMChemogenomic Deduction of Escherichia coli's Nitric Oxide Response Network
Daniel R. Hyduke, Laura R. Jarboe, Linh M. Tran, James C. Liao
1:30 PMSignaling Pathways Affecting Sporulation and Stationary Phase Phenomena in Clostridium Acetobutylicum
Ryan Sillers, Mohab Al-Hinai, Carlos J. Paredes, Eleftherios T. Papoutsakis
1:50 PMBreak
2:00 PMTranscriptional Regulation Underlying the Central Nervous System Response to Acute Hypertension
Rajanikanth Vadigepalli, Rishi Khan, James S. Schwaber
2:20 PMComparative Transcriptome Analysis of Stem Cell Populations Expressing Varying Levels of the Transcription Factor Oct-4
Fernando Ulloa-Montoya, Catherine Verfaillie, Wei-Shou Hu
2:40 PMComprehensive Analysis of the Gluconeogenesis Pathways through the Combined Use of Multiple Isotopic Tracers
Maciek R. Antoniewicz, Jose Aleman, Joanne K Kelleher, Gregory N. Stephanopoulos

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