Tuesday, November 14, 2006: 8:30 AM-11:00 AM
Continental 7 (Hilton San Francisco)
#169 - Advances in Protein Engineering (I) (15C02)
The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) Protein engineering via directed evolution; (4) Structure- or sequence-based and computational protein engineering and design; (5) Applications of protein engineering.
Chair:Lianhong Sun
CoChair:Scott Banta
8:30 AMUnderstanding the Reaction Mechanism of Protein Splicing in Order to Gain Insights for the Engineering of Inteins
Brian Pereira, Philip Shemella, Patrick Van Roey, Marlene Belfort, Victoria Derbyshire, Saroj Nayak, Georges Belfort, Shekhar Garde
8:50 AMAntibody Affinity Maturation Using Computational Protein Design
Shaun M. Lippow, Bruce Tidor, K. Dane Wittrup
9:10 AMComputation-Guided Design of Arac Regulatory Protein Effector Specificity
Hossein Fazelinia, Patrick C. Cirino, Costas D. Maranas
9:30 AMApplication of the Consensus Concept for Increased Thermostability of Enzymes
Eduardo Vazquez-Figueroa, Javier Chaparro-Riggers, Karen M. Polizzi, Andreas S. Bommarius
9:50 AMBreak
10:00 AMBioinformatics-Mediated Rational Approaches to Protein Engineering for Increased Stability
Philippa J. Reeder, Christopher Bystroff, Jonathan S. Dordick
10:20 AMEngineering Transcription Factors with Novel DNA-Binding Specificity Using Comparative Genomics
Tasha Desai, Christopher V. Rao
10:40 AMGenetic Selection of Stable Single-Chain Immunotherapeutics in the Cytoplasm of Escherichia Coli
Adam C. Fisher, Matthew P. DeLisa

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