Monday, November 13, 2006: 3:15 PM-5:45 PM
Continental 8 (Hilton San Francisco)
#115 - Advances in Protein Expression and Post-Translational Modification (15C20)
Increasing demand for recombinant proteins has focused research on techniques for improving protein expression and controlling post-translational processing. We invite papers on all aspects of protein expression including novel cell systems, expression vectors, and culture conditions. Submissions dealing with post-translational processing including glycosylation, editing and secretion are also invited. Papers may deal with any cell type including bacteria, yeast, mammalian, insect and plant cell cultures.
Chair:Matthew P. DeLisa
CoChair:Jennifer A. Maynard
3:15 PMExceptional Total and Functional Yields of the Human Adenosine a2a Receptor Expressed in the Yeast Saccharomyces Cerevisiae
Michelle O'Malley, Ronald Niebauer, Anne Skaja Robinson
3:35 PMEnabling Biosynthesis of Complex Proteins in Bacteria Via Ribosome Reprogramming
Lydia M. Contreras, Matthew P. DeLisa
3:55 PMHumanization and Structural Studies to Tailor the Efficiency of Pertussis Toxin (Pt) Neutralizing Antibodies
Kavita Ramalingam Iyer, Jennifer A. Maynard
4:15 PMCellular and Protein Engineering Approaches for Increasing Human Brain-Derived Neurotrophic Factor Production in Yeast
Michael L. Burns, Eric Shusta
4:35 PMBreak
4:45 PMEngineering Membrane Protein Biogenesis
A. James Link, Nandini S. Aiyappan, George Georgiou
5:05 PMDirected Evolution of a G-Protein Coupled Receptor
Casim A. Sarkar, Andreas Plueckthun
5:25 PMCell-Free Protein Synthesis of Complex Proteins Containing Unnatural Amino Acids
Aaron R. Goerke, Jessica J. Wuu, James R. Swartz

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