Wednesday, November 15, 2006: 3:15 PM-5:45 PM
Union Square 23 (Hilton San Francisco)
#419 - (22b) Bionanotechnology for Gene and Drug Delivery (T8012)
Bionanotechnology uses concepts from chemistry, physics, and molecular biology to identify components and processes for the construction of nanomaterials and nanodevices for health care. This session invites papers that focus on the design and development of nanomaterials and nanodevices for gene and drug delivery. Topics of interest include, but are not limited to: novel methods and compositions to design gene and drug delivery systems at the nanoscale level, and the effects of the sizes of gene and drug delivery systems on gene and drug release kinetics, and pharmacokinetics, cellular uptake, biological transport, and bioefficacy of gene- and drug-carrier complexes.
Chair:Tao L. Lowe
CoChair:Junghae Suh
3:15 PMFolate Conjugated Polymer Micelles Formulated with TPGS for Selective Tumor Targeting
Haizheng Zhao, Lin Yue Lanry Yung
3:34 PMCationic B-Cyclodextrin Polymers for Controlled Drug Delivery across the Blood Brain Barrier (Bbb)
Eun Seok Gil, Tao L. Lowe, Jianshu Li, Huining Xiao
3:53 PMSearching for Optimal Properties of Synthetic Gene Vectors Via Simulations of Intracellular Transport Processes
Chinmay Pangarkar, Anh-Tuan Dinh, Theo Theofanous, Samir Mitragotri
4:12 PMHydrodynamic Self-Assembly of DNA-Pei Nanoparticles in a Microfluidic System for Gene Delivery
Chee Guan Koh, Jingjiao Guan, Zhengzheng Fei, Yubing Xie, Bo Yu, Yihua Loo, Kam W. Leong, L. James Lee
4:31 PMBreak
4:50 PMEfficient Nuclear Delivery of Antisense Oligo-Nucleotides by Neutral, Self-Porating Polymersomes
Younghoon Kim, Manu Tewari, David Pajeroski, Shamik Sen, Williams Jason, Shashank Sirsi, Gordon Lutz, Dennis E. Discher
5:09 PMCore-Shell Drug Nanoparticles for Therapeutic Delivery
Alisar S. Zahr, Michael V. Pishko
5:27 PMBiodegradable Biphasic Nanocarriers for Multiple Drugs Delivery with Complex Release Profiles in a Controlled Manner
Kyung-Ho Roh, Sridhar Valluri, Joerg Lahann

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