Tuesday, November 14, 2006: 8:30 AM-11:00 AM
Continental 2 (Hilton San Francisco)
#195 - Membranes for Bioseparations I (02D09)
This session will concentrate on the theoretical principles and practical considerations that underlie the use of membranes in the downstream processing of biopharmaceutical products (e.g. microfiltration, ultrafiltration, nanofiltration, virus filtration, and membrane chromatography). Papers describing advances in membrane processes, new membrane materials and applications, and case studies of membrane systems in the biopharmaceutical industry are sought.
Chair:Andrew Zydney
CoChair:Nuno Fontes
8:30 AMEffects of pH and Ionic Conditions on Microfiltration of Mammalian Cells: Combined Permeate Flux Enhancement and Mab Purification Capabilities
Jonathan Karl Romero, Philippe de Vilmorin, James Chrostowski
8:50 AMImproving Permeate Flux in the Microfiltration of a Bacterial Cell Suspension by Flocculation with Cationic Polyelectrolytes
Matthew T. Aspelund, Charles E. Glatz, Kevin M. Graves, Glenn Rozeboom, Meng Heng
9:10 AMProtein Fouling of Microfiltration Membranes in in-Line Modules
Dharmesh Kanani, Raja Ghosh
9:30 AMSmart Monomers and Nature-Inspired Monomers for Protein Adhesion-Resistant Membranes
Arpan Nayak, Hongwei Liu, Georges Belfort
9:50 AMOrganic-Inorganic Hybrid Membranes for Protein Purification
Daniel F. Shantz, Seunguk Yeu
10:10 AMViral Filtration of High-Titer Mab Solutions with Hollow Fiber Membranes
Bruno F. Marques, Nihal Tugcu, M. Ellen Dahlgren, Sarah Parola, David J. Roush
10:30 AMVirus Capture by Tangential Flow Filtration
Ranil Wickramasinghe, David Grzenia, Peter Czermak

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