A land-based wastewater management system, often referred to as land application, is a cost-effective, natural way to reuse wastewater and its associated pollutants in a soil/crop system by applying the water in a controlled manner. The area to which the water is applied is managed so that constituent loadings are at or slightly below the agronomic and hydraulic uptake rates of the designated soil/crop system. There are many economic and environmental benefits of land applying wastewater. The benefits of using land application versus other treatment and discharge methods can include lower capital investment, lower maintenance, lower energy, reduced system upsets, potential opportunities for local revenue improvements, and net water savings. This paper reviews the principal challenges and solutions for incorporating land application as part of a wastewater management strategy and provides several examples of where this approach was successfully used for managing discharges from municipalities, food-processing plants, the oil and gas industry, and power-generating facilities.