| Thursday, 3 November 2005: 3:15 PM-5:45 PM | |||
| Regency Ballroom G (Hyatt Regency Cincinnati) | |||
Bioengineering (15c) | |||
| #533 - Advances in Systems Biology: Computational Methods and Applications (15C00) | |||
| Developments in high throughput technologies have allowed for rapid improvement of many biological species and systems including enzymes, protein complexes, cellular pathways and whole organisms. The current challenge is how to apply these technologies for enabling discoveries in many diverse areas of biochemical technology such as metabolic engineering, drug discovery, tissue engineering, and bioprocess development. This session will include contributions that describe applications of existing technologies (e.g. directed evolution, genomic and proteomic information in cellular and metabolic engineering), improvement and development of new technologies and methodologies (e.g. new combinatorial display techniques, improvements in proteome and transcriptome technologies), and computational and mathematical frameworks for the quantitative analysis of the available information (e.g. computational approaches to library construction and prescreening, systems engineering application on biological systems, computational methods for prediction of protein structure and function). | |||
| CoChair: | Matthew DeLisa | ||
| Chair: | Charles Roth | ||
| 3:15 PM | 533a | Generalization of Network Component Analysis Linh My Tran, Simon J. Galbraith, James C. Liao | |
| 3:35 PM | 533b | Mixed-Integer Reformulations of Network Component Analysis Eric Yang, Joseph Vitolo, Charles Roth, Ioannis (Yannis) P. Androulakis | |
| 3:55 PM | 533c | Data Integration and Bioinformatics in the Analysis of Developing Tissues Chris A. Bristow, Nir Yakoby, Rachel Kalifa, Gertrud Schupbach, Stas Shvartsman | |
| 4:15 PM | 533d | An Optimization Framework for Identifying Reaction Activation/Inhibiton or Elimination Candidates for Overproduction in Microbial Systems Priti Pharkya, Costas D. Maranas | |
| 4:35 PM | Intermission | ||
| 4:45 PM | 533e | Analysis of the Thermodynamic Feasibility of a Genome Scale Metabolic Model Matthew D. Jankowski, Christopher Henry, Linda Broadbelt, Vassily Hatzimanikatis | |
| 5:05 PM | 533f | A New Milp Based Approach for in Silico Reconstruction of Metabolic Networks and Its Application to Marine Cyanobacterium Prochlorococcus Marinus Xiaoxia (Nina) Lin, Aaron Brandes, Jeremy Zucker, George M. Church | |
| 5:25 PM | 533g | Sensitivity Analysis in Biological Modeling: an Application in the Model Development of Staphylococcal Enterotoxin B Pre-Apoptotic Pathways Rudiyanto Gunawan, Stephanie R. Taylor, Francis J. Doyle III | |
| Sponsor: | Food, Pharmaceutical & Bioengineering Division | ||
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