Thursday, 3 November 2005: 12:30 PM-3:00 PM
Regency Ballroom C (Hyatt Regency Cincinnati)

Topical H – Biological Applications of Nanotechnology (Bionanotechnology) (TH)

#489 - Bionanotechnology for Gene and Drug Delivery II (TH012)
Bionanotechnology uses concepts from chemistry, physics, and molecular biology to identify components and processes for the construction of nanomaterials and nanodevices for health care. This session invites papers that focus on the design and development of nanomaterials and nanodevices for gene and drug delivery. Topics of interest include, but are not limited to: novel methods and compositions to design gene and drug delivery systems at the nanoscale level, and the effects of the sizes of gene and drug delivery systems on gene and drug release kinetics, and pharmacokinetics, cellular uptake, biological transport, and bioefficacy of gene- and drug-carrier complexes.
CoChair:Qiang Wang
Chair:Junghae Suh
12:30 PMDegradable Polymersomes That Create New Pathways for Anti-Cancer Drugs
Fariyal Ahmed, Refika I. Pakunlu, Goundla Srinivas, Michael L. Klein, Tamara Minko, Dennis E. Discher
12:45 PMBreaking down Endolysosomal Barriers for Drug Delivery with Degradable Polymersomes
Fariyal Ahmed, Goundla Srinivas, Aaron Brannan, Michael L. Klein, Frank S. Bates, Dennis E. Discher
1:00 PMControlled Transdermal Nicotine Delivery with Aligned Carbon Nanotube Membrane
Bruce J. Hinds, Audra Stinchcomb, Mainak Majumder, Nitin Chopra
1:15 PMReal-Time Transport of Polymer Nanoparticles in Cervical Vaginal Mucus
Samuel K. Lai, Elizabeth D. O’Hanlon, Stan T. Man, Richard Cone, Justin Hanes
1:30 PMVirus Engineering for Targeted Gene Delivery
Pin Wang, Leslie Bailey, Kendra Rideout
1:45 PMEnhanced Adhesion of Anti-E-Selectin Biodegradable Nanoparticles to Tnf-Α Activated Endothelium in Vitro and in Vivo
Harshad S. Sakhalkar, Jie Fu, Sudhir P. Deosarkar, Xiaoyan Zou, Mark Christman, Justin Hanes, David T. Kurjiaka, Douglas J. Goetz
2:00 PMStability of High Density Pei/Vegf DNA Nanocomplexes in Physiological Fluids
Yah-el Har-el, John H. Van Zanten, Justin Hanes
2:15 PMA Computational Model of Transient Drug/Chemical Diffusion through Human Skin in the Vicinity of a Hair Follicle
Yuri H. Dancik, Gerald B. Kasting, Johannes M. Nitsche
2:30 PMConvection Enhanced Drug Infusion into the Soft Brain Tissue
Michalis Xenos, Xuedong Zhou, MahadevaBharath R. Somayaji, Andreas A. Linninger
Sponsor:Topical H – Biomedical Applications of Nanotechnology (Bionanotechnology)
Cosponsors:Food, Pharmaceutical & Bioengineering Division

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