Tuesday, 1 November 2005: 12:30 PM-3:00 PM
Bronze Ballroom A (Millennium Hotel)

Topical A - American Electrophoresis Society Annual Meeting (TA)

#197 - Advances in Proteomic Analysis: Focus on Bioinformatics (TA004)
Proteomics technologies generate dauntingly large amounts of heterogeneous data types, and thus, are highly dependent on, and integrated with, informatics.  This session will cover a broad range of topics in Bioinformatics related to Proteomics.  Laboratory information management systems (LIMS), image analysis systems and databases are needed for generation and maintenance of proteomics data.  Data and image storage systems are needed in addition to "encyclopedia" type systems that catalog results.  Fundamental questions regarding formats for data exchange and storage as well as architectures for archiving public proteomics data are still being formulated.  Simple aggregation of proteomics data as well as the more challenging integration of datasets both within proteomics and between proteomics and other disciplines (genomics, metabolomics) are still in their infancy.  A broad range of specialized tools are needed for analysis of proteomics data, including statistical analysis and pathway mapping. Finally to fully exploit the data to advance our knowledge and understanding of biology we need new intelligent systems to aid data interpretation and hypothesis generation.  As the proteomics and bioinformatics communities focus their efforts on develping the necessary computational and informatics infrastructure,  a rapidly growing open source effort has arisen to more effectively address the need for standards and new computational tools.
CoChair:Philip Andrews
Chair:Ruth Vanbogelen
12:30 PM197aPlenary: High Throughput Proteomics Informatics Challenges
Gordon A. Anderson, Ken J. Auberry, Gary R. Kiebel, Mathew E. Monroe, Elena S. Peterson, Eric F. Strittmatter, Nikola Tolic
1:00 PM197bAgml Central: a Proteomic Infrastructure for the Representation, Storage and Analysis of 2-D Gel Electrophoresis Data
Romesh Stanislaus, C Chen, John Arthur, Jonas S. Almeida
1:15 PM197cBioinformatics and Proteomics Approaches Towards Defining the Proteome of Chloroplast Envelope Membranes
Andreas P.M. Weber, Susanne Hoffmann-Benning, Andrea Bräutigam
1:30 PM197dThe Microbial Proteome Project: a Database of Microbial Protein Expression in the Context of Genome Analysis
Carol S. Giometti, Sandra Tollaksen, Tripti Khare, Angela Ahrendt, Carl Lindberg, John Yates III, Gyorgy Babnigg
1:45 PM197ePlenary: the Human Protein Interaction Network
Joel S. Bader
2:15 PM197fFrom Experimental Data to Mechanistic Hypotheses: Analysis of Proteomic Data Using a Very Large-Scale Causal Model
Dexter R. Pratt
2:30 PM197gKnowledge-Based Computational Pathways Analysis for Integrative Drug Discovery
Ramon M. Felciano
2:45 PM197hAccelerated Evolution of Genes and Neocortical Expansion in Mammalian Lineages
Lawrence I. Grossman, Derek E. Wildman, Juan C. Opazo, Morris Goodman
Sponsor:Topical A - American Electrophoresis Society Annual Meeting

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