| Tuesday, 1 November 2005: 8:00 AM-10:30 AM | |||
| Bluegrass B (Hyatt Regency Cincinnati) | |||
Topical 4 - Systems Biology (T4) | |||
| #149 - - Synthetic Systems Biology (T4004) | |||
| Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest. | |||
| CoChair: | Jay D. Keasling | ||
| Chair: | Christina Smolke | ||
| 8:00 AM | 149a | Construction and Evolution of an Artificial Microbial Symbiotic System Nikos Reppas, Xiaoxia (Nina) Lin, Jay Shendure, Greg Porreca, George M. Church | |
| 8:20 AM | 149b | Sources of Switch-like Behavior in Simple and Complex Biochemical Networks: Understanding the Action of a Cancer Target, Dihydrofolate Reductase Martin R. Feinberg, Yangzhong Tang, Gheorghe Craciun, Jeffrey Chalmers, Timothy Mitchison | |
| 8:40 AM | 149c | Benefits and Costs of Improving Stress Tolerance Jeanne M. Bonomo, Ryan T. Gill | |
| 9:00 AM | 149d | Tuning Resistance in the Map Kinase Pathway: Lessons for Synthetic Biology from a Developmental Network in C. Elegans Claudiu Giurumescu, Stephen Chapman, Anand R. Asthagiri | |
| 9:20 AM | 149e | A Synthetic E.Coli Predator-Prey System Jun Ozaki, Matthew Barnet, Cynthia H. Collins, Frances H. Arnold, Lingchong You | |
| 9:40 AM | 149f | A Synthetic Gene-Metabolic Oscillator Eileen Fung, Wilson W. Wong, Jason K. Suen, Thomas Buelter, Sungu Lee, James C. Liao | |
| 10:00 AM | 149g | "Directed" Directed Evolution: a Simple Method for Incorporating Sequence Information to Improved Directed Evolution Experiments Kyle L. Jensen, Hal Alper, Curt Fischer, Gregory Stephanopoulos | |
| Sponsor: | Topical 4 - Systems Biology | ||
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