Tuesday, 1 November 2005: 8:00 AM-10:30 AM
Regency Ballroom F (Hyatt Regency Cincinnati)

Engineering Fundamentals in Life Science (15d)

#191 - Transport Phenomena in Tissue Engineering (15D12)
The field of tissue engineering seeks to create clinically effective materials for the repair of damaged tissues and organs and the treatment of medical conditions brought on by trauma, disease or congenital defects. Tissue engineering strategies involve the incorporation of novel biomaterials with biologics and/or pharmaceutics, that upon implantation in the patient will stimulate angiogenesis, tissue integration, and/or tissue remodeling. Critical to the development of effective tissues is the regulation of transport phenomena. This includes delivery of oxygen, nutrients, transforming factors, genes, and cryoprotectants to cells, clearance of metabolic waste products, and intercellular communication via autocrine and paracrine factors. Concurrently, transport of cells represents another challenging component of tissue engineering and important considerations include the migration of cells through scaffolds and their spatial organization into tissue structures. This session seeks a broad range of research abstracts that encompass both experimental and computational aspects of transport phenomena. Tissues include but are not limited to liver, pancreas, retina, muscle, skin, tendon, cartilage, bone, vascular, and nerve.
CoChair:Vassilios I. Sikavitsas
Chair:Aaron S. Goldstein
8:00 AMMass Transfer Rates and Initial Conditions Modulate the Growth Rates and Structure of Bioartificial Tissues
Kyriacos Zygourakis, Jian Feng, Pauline A. Markenscoff
8:20 AMStrategies to Enhance Capillary Formation inside Biomaterials: a Computational Study
Ehsan Jabbarzadeh, Cameron F. Abrams
8:40 AMTraceable Hil2 Secretion in Enyzme Crosslinked Gelatin Cellular Scaffolds
Chong Wing Yung, Timothy Barbari, William E. Bentley, Gregory F. Payne
9:00 AMModulation of Liver Functions Expressed by Hepg2 Cells by Limiting Oxygen Diffusion
James P. Camp, Adam T. Capitano
9:20 AMIntermission
9:30 AMPerfluorocarbons for Enhanced Oxygen Transport in Tissue Engineering Devices
Kyuongsik Chin, Surita R. Bhatia, Susan C. Roberts
9:50 AMProtection of Microencapsulated Islets from Hypoxia by Perfluorocarbon
Amy S. Lewis, Robert J. Fisher, Abdulkadir Omer, Gordon C. Weir, Clark K. Colton
10:10 AMCharacteristics of Btc Tet Cells for Use in the Cryopreservation of a Model Tissue Engineered Pancreatic Substitute
Indra Neil Mukherjee, Ying Ching Song, Athanassios Sambanis
Sponsor:Food, Pharmaceutical & Bioengineering Division
Cosponsors:Materials Engineering and Sciences Division

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