| Thursday, 3 November 2005: 12:30 PM-3:00 PM | |||
| Regency Ballroom G (Hyatt Regency Cincinnati) | |||
Bioengineering (15c) | |||
| #487 - Advances in Systems Biology: Experimental Methods and Applications (15C17) | |||
| Developments in high throughput technologies have allowed for rapid improvement of many biological species and systems including enzymes, protein complexes, cellular pathways and whole organisms. The current challenge is how to apply these technologies for enabling discoveries in many diverse areas of biochemical technology such as metabolic engineering, drug discovery, tissue engineering, and bioprocess development. This session will include contributions that describe applications of existing technologies (e.g. directed evolution, genomic and proteomic information in cellular and metabolic engineering), improvement and development of new technologies and methodologies (e.g. new combinatorial display techniques, improvements in proteome and transcriptome technologies), and computational and mathematical frameworks for the quantitative analysis of the available information (e.g. computational approaches to library construction and prescreening, systems engineering application on biological systems, computational methods for prediction of protein structure and function). | |||
| CoChair: | Charles M. Roth | ||
| Chair: | Matthew P. DeLisa | ||
| 12:30 PM | 487a | Genomics Tools for Elucidating the Function of Trait Conferring Genes Michael D. Lynch, Tanya Warnecke, Amarjeet Singh, Ryan T. Gill | |
| 12:50 PM | 487b | Proteomics-Based Systems Biology Study of the Phosphorus Starvation Response in the Cyanobacterium Synechocystis Sp. Strain Pcc6803 Chee Sian Gan, Nigel G. Ternan, Geoffrey McMullan, Kenneth F. Reardon, Phillip C. Wright | |
| 1:10 PM | 487c | Enabling Cell Factory Design through High-Throughput and Quantitative Metabolome Analysis Michael C. Jewett, Jens Nielsen | |
| 1:30 PM | 487d | Study of Heat Shock Effects on Inflammatory Signaling Using a Microfluidic Living Cell Array Sihong Wang, Kevin R. King, Kenneth J. Wieder, Mehmet Toner, Arul Jayaraman, Martin L. Yarmush | |
| 1:50 PM | Intermission | ||
| 2:00 PM | 487e | A High-Throughput Screen for Poly-3-Hydroxybutyrate for Inverse Metabolic Engineering of Recombinant Escherichia Coli and Synechocystis Pcc 6803 Keith E. Tyo, Hang Zhou, Hal S. Alper, Gregory Stephanopoulos | |
| 2:20 PM | 487f | Systematic Analysis of Erbb Induced Signaling, Proliferation, and Migration Neil Kumar, Alejandro Wolf-Yadlin, Forest White, Douglas Lauffenburger | |
| 2:40 PM | 487g | High Throughput Approach to Drug Discovery: Sars Coronavirus - a Case Study Dhaval N. Gosalia, Graham Simmons, Scott L. Diamond, Paul Bates | |
| Sponsor: | Food, Pharmaceutical & Bioengineering Division | ||
| Cosponsors: | Computing and Systems Technology Division | ||
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