Thursday, 3 November 2005: 12:30 PM-3:00 PM
Buckeye A (Hyatt Regency Cincinnati)

Engineering Fundamentals in Life Science (15d)

#506 - Intracellular Processes (15D06)
The focus of this session is the quantitative analysis of intracellular processes at the molecular level, including but not limited to studies of signal transduction, cytoskeletal dynamics, protein trafficking, gene expression, and metabolic and transcriptional networks. Experimental studies and data-driven or theoretical models of intracellular processes, including the analysis of cell biochemical and subcellular imaging data, will be highlighted. The session will consist of 15-20 minute talks by 7-10 speakers selected from abstracts submitted to the session.
CoChair:Jason M. Haugh
Chair:Chetan J. Gadgil
12:30 PM506aAltered Egfr Trafficking and Signaling in Iressa-Sensitive Human Cell Lines
Matthew J. Lazzara, Paul Jasper, Peter Sorger, Douglas A. Lauffenburger
12:50 PM506bExperimentation, Modeling and Parameter Sensitivity Analysis Suggest a Role of Erk in Receptor down-Modulation during T Cell Signaling
Yanan Zheng, Marietta Harrison, Ann Rundell
1:10 PM506cCell Fate Determination by Multiple Signaling Pathways: Genome-Wide Analysis and Modeling of Pattern Formation in Drosophila Egg Development
Nir Yakoby, Chris A. Bristow, Rachel Kalifa, Gertrud Schupbach, Stas Shvartsman
1:30 PM506dApoptotic Signaling Pathways in Megakaryocytes
Lisa M. Giammona, Eleftherios T. Papoutsakis, William M. Miller
1:50 PM Intermission
2:00 PM506eTopology and Dynamics of Pro-Mitogenic Β-Catenin Signaling in Mammary Epithelial Cells
Nicholas A. Graham, Anand R. Asthagiri
2:20 PM506fDetermination and Analysis of the Dynamic Mechanisms That Precede Long-Term Depression in Cerebellar Purkinje Cells
Nicholas Hernjak, Boris M. Slepchenko, Leslie M. Loew
2:40 PM506gModeling of Heterotrimeric G-Protein Mediated Calcium Response in Raw 264.7 Macrophage Cells
Mano R. Maurya, Shankar Subramaniam
Sponsor:Food, Pharmaceutical & Bioengineering Division

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