| Tuesday, 1 November 2005: 3:15 PM-5:45 PM | |||
| Regency Ballroom E (Hyatt Regency Cincinnati) | |||
Engineering Fundamentals in Life Science (15d) | |||
| #260 - Engineering Approaches in Gene Delivery (15D05) | |||
| This session will focus on application of engineering principles towards the fulfillment of gene therapy as a therapeutic modality. Talks related to both viral and non-viral delivery approaches are encouraged. Presentations devoted to the development of improved methods of gene transfer and to the analysis of extracellular and intracellular transport and reaction processes are of interest, as are those related to the standardization of gene transfer assays and the processing of gene transfer vectors. Specific topics of interest include, but are not limited to: design and synthesis of novel formulations and systems for improved gene delivery; experimental measurement and quantitative modeling/analysis of vector-cell interactions and intracellular trafficking; effects of processing and storage conditions on gene transfer vectors; novel assays for monitoring of gene transfer steps or clinical efficacy. | |||
| CoChair: | Lonnie D Shea | ||
| Chair: | Daniel W. Pack | ||
| 3:15 PM | 260a | Self-Assembling Linear-Dendritic Hybrid Polymers for Receptor-Mediated Gene Delivery Kris C. Wood, Robert Langer, Paula T. Hammond | |
| 3:35 PM | 260b | Quantitative Evaluation of the Role of Vector in the Dynamics of Antisense Effects Sumati Sundaram, Li Kim Lee, Charles Roth | |
| 3:55 PM | 260c | Short and Long Time Dynamics of Synthetic Gene Vectors in Mammalian Cells Chinmay H. Pangarkar, Tuan A. Dinh, Samir Mitragotri | |
| 4:15 PM | 260d | Engineering Substrate-Mediated Gene Delivery with Self-Assembled Monolayers Angela K. Pannier, Lonnie D. Shea | |
| 4:35 PM | Intermission | ||
| 4:45 PM | 260e | Engineering Bacterial Outer Membrane Vesicles for DNA Vaccine Delivery David Chen, Jae-Young Kim, Anne M. Doody, Matthew DeLisa, David Putnam | |
| 5:05 PM | 260f | A Viral/Non-Viral Hybrid Gene Delivery Vector Josh Ramsey, Daniel W. Pack | |
| 5:25 PM | 260g | Directed Evolution of Aav to Generate Mutants with Enhanced Transport Properties James T. Koerber, Narendra Maheshri, David V. Schaffer | |
| Sponsor: | Food, Pharmaceutical & Bioengineering Division | ||
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