| Wednesday, 2 November 2005: 8:00 AM-10:30 AM | |||
| Buckeye A (Hyatt Regency Cincinnati) | |||
Engineering Fundamentals in Life Science (15d) | |||
| #304 - Biomedical Applications of Systems Biology (15D04) | |||
| Systems biology, which stands at the nexus of biological and computational sciences and engineering, offers the promise of systematically studying biological systems, not only in a descriptive manner but also with predictive ability. The comprehensive classification and comparison of biomolecular sequences, structures and functions can guide the development of statistical methods and computational predictive tools and experimental approaches that will provide new insights and opportunities to improve human condition. Experimental methods that enable systematic exploration of living organisms are resulting to the rapid transformation of biology to a data-driven science. This necessitates the development of mathematical/computational modeling and data mining algorithms and that will enable scientists and engineers to seamlessly harness biological information and extract knowledge to guide the development of therapeutic and biotechnology solutions. We are inviting presentations on both experimental and theoretical aspects of systems biology research. Of specific interest are presentations that combine both approaches to generate a comprehensive picture of biological problems. | |||
| CoChair: | Yiannis Kaznessis | ||
| Chair: | Arul Jayaraman | ||
| 8:00 AM | 304a | Genome-Scale Analysis of Translation in S. Cerevisiae: Insights into System Response and Regulation Vassily Hatzimanikatis, Amit Mehra | |
| 8:20 AM | 304b | Computational Analysis of Combinatorial Gene Regulation in the Liver Joseph L. Vitolo, Ioannis (Yannis) P. Androulakis, Charles M. Roth | |
| 8:40 AM | 304c | Graph Theory-Flux Analysis Framework for Tissue-Specific Modeling of Metabolic Network Structure and Function Ryan P. Nolan, Yaguang Si, Kyongbum Lee | |
| 9:00 AM | 304d | Knowledge-Based Integration of Metabolic and Genetic Information to Identify Targets of Fatty Acid Toxicity Shireesh Srivastava, Christina Chan | |
| 9:20 AM | Intermission | ||
| 9:30 AM | 304e | Advances in Metabolic Flux Analysis from Stable Isotope Experiments: Theory and Applications Maciek R. Antoniewicz, Joanne K. Kelleher, Gregory Stephanopoulos | |
| 9:50 AM | 304f | Megakaryocyte Development Illuminated by Transcriptional Analysis Peter G. Fuhrken, Chi Chen, William M. Miller, Eleftherios T. Papoutsakis | |
| 10:10 AM | 304g | Identification of Important Signaling Proteins and Stimulants for the Production of Cytokines in Raw 264.7 Macrophages Sylvain Pradervand, Mano R. Maurya, Shankar Subramaniam | |
| Sponsor: | Food, Pharmaceutical & Bioengineering Division | ||
| Cosponsors: | Computing and Systems Technology Division | ||
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