Thursday, November 8, 2007: 3:30 PM-6:00 PM
Room 251 F (Salt Palace Convention Center)

Pilot Plants (12b)

#648 - Strategies in Pharmaceutical Scale-up and Pilot Plants (12B04)
Pilot plants play a key role in the overall pharmaceutical process development scheme. This session is interested in topics that address unique approaches to scale-up challenges and troubleshooting, novel technology transfer strategies, plant operation and design, statistical control for process optimization and implementation, novel implementation of Process Analytical Technology (PAT) on scale, etc.
Chair:Brent Nielsen
CoChair:Elizabeth Spiteri
3:30 PMTroubleshooting and Performance Recovery of a Pharmaceutical Manufacturing Process Involving a Novel Asymmetric Hydrogenation and a Chiral Crystallization
Osama Sudah, Aaron Moment, Carlos Burgos, Cindy Starbuck, Andrew Clausen, Mahmoud Kaba, Carlos Sanchez, Ryan Adorno, Mabel Suarez, Alvin Negron, Luis Sierra, Ramon Huertas
3:50 PMControl of a Membrane Separation Process by UV / Vis P.a.T
James Marek, Eric Stoner, James Schilling
4:10 PMExpedite Development and Commercialization of Pharmaceuticals with Process Modeling and Scheduling Tools
Demetri Petrides, Charles Siletti
4:30 PMBreak
4:40 PMModeling Based Approach towards on-Scale Implementation of a Methanethiol Emitting Reaction
Brenda Remy, Shawn Brueggemeier, Olav Lyngberg, D Lin, Alex Marchut, L Hobson
5:00 PMApplications of Mass Spectrometry for Monitoring Gaseous Streams during Processing
John P. Gardner, Jacob R. Remacle, Steven J. Doherty, Daniel J. Creeden, Kevin D. Seibert, Zhonghui Wan, Amanda L. Mc Daniel, John P. Schafer, Gary A. Richardson
5:20 PMA Quality by Design Qbd Approach for Pharmaceutical Capsule Filling Unit Operation: Identifying Critical Process Variables and Detecting Possible Interactions
Huiquan Wu, Lin Xie, Meiyu Shen, Mansoor A. Khan, Larry Augsburger, Stephen W. Hoag

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See more of The 2007 Annual Meeting