Monday, November 5, 2007: 3:30 PM-6:00 PM
Room 355 F (Salt Palace Convention Center)

Topical 3: 2007 Annual Meeting of the American Electrophoreses Society (AES) (T3)

#119 - Biomems and Microfluidics: Cell and Biomolecule Analysis (T3011)
The ability to study cellular processes at the single-cell level promises to provide a host of information with benefits in the area of therapeutics and drug discovery. This session will focus on all aspects related to emerging concept of ‘cells in chips’ that is driven by the need to use microfluidics to (1) control cellular environment with fine spatial and temporal resolution (2) parallelize and automate cell-based analysis (3) integrate sensitive detection methods for intracellular components and whole cells. In particular, research studies involving integrated microfluidic approaches to single-cell analysis for disease diagnostics are of special interest. These may incorporate live cell biochemical (metabolites, electrolytes, ions) or physical (morphology and mechanics) measurements. In this session, we invite papers describing microfluidic technology to probe chemical and biochemical responses at the cellular and sub-cellular levels. In addition, we welcome fundamental studies focused on any related aspects including simulation and modeling studies, materials modification to improve system performance, substrate biochemistry, cellular rheology and novel sample preparation protocols.
Chair:Nimisha Srivastava
CoChair:Siva A. Vanapalli
3:30 PMSingle Molecule Lamda-DNA Stretching Studied by Microfluidics and Single Particle Tracking
Jun Wang, Chang Lu
3:50 PMChemotaxis of E. Coli in a Microfluidic Device: Experiments and Simulations
Rajitha Vuppula, Mahesh S. Tirumkudulu, K. V. Venkatesh
4:10 PMMicrofluidic Devices For Local Rheological Characterization Of Viscoelastic Biological Materials
Danial N. Hohne, John G. Younger, Michael J. Solomon
4:30 PMLinear Amplification Of Mrna Using Microfluidic Systems For Gene Expression Analysis
Jason G. Kralj, Audrey Player, Ernest Kawasaki, Laurie E Locascio
4:50 PMLabel-Free DNA Detection In Microchannels By A Reversible Light Diffracting Mesophase
Faisal Shaikh, Victor M. Ugaz
5:10 PMIntegrated Micro System For High Resolution Imaging And High-Throughput Sorting Of C. Elegans
Kwanghum Chung, Matthew Crane, Lu Hang
5:30 PMGeneration Of Microenvironments With Controlled Mechanical Properties For Analysis Of Mouse Embryonic Stem Cell Fate
Bong Geun Chung, Benjamin S. Gillers, Shamit Shrivastava, Ali Khademhosseini

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