Tuesday, November 6, 2007: 3:30 PM-6:00 PM
M - Salon D (Marriott Salt Lake City-Downtown)

Topical I: Pharmaceutical Engineering for the 21^st Century (TI)

#307 - Modeling in the Pharmaceutical Industry (TI007)
We invite contributions from industry and academia that address system-level process simulation (cycle time analysis, mass and energy balances, equipment usage, scheduling etc.) and/or more detailed unit operations modeling during process development and scale-up in pharmaceutical synthesis and formulation (e.g. reaction steps, solvent chasing, crystallization, filtration, drying). Particular consideration will be given to examples of model development from laboratory data with model validation during scale-up and clear savings or greater process understanding as a result of modeling.
Chair:Victor Hung
CoChair:Joe Hannon
CoSponsor(s):Pharmaceuticals (15b)
3:30 PMOpportunities, Challenges, And Approaches For Modeling In The Pharmaceutical Industry
Prashant B. Kokitkar
3:50 PMModeling of Breakage and Dissolution of Crystals with Varying Particle Size Distribution within the Quality by Design Framework
Pavol Rajniak, Kim Gallagher, Rey Chern, Craig Ikeda, Justin Moser
4:10 PMApplication of Modeling in a Qbd Context
James Wertman
4:30 PMCoater-Dryer Models
Alexander J. Marchut, Wei Chen, Steven H. Chan, Shih-Ying Chang, Olav Lyngberg, Donald Kientzler, San Kiang
4:50 PMBreak
5:00 PMPotential of S88, Batchml and Other Standards in Streamlining Process Modeling
Alistair Gillanders
5:20 PMBatch Plus Modeling As A Tool To Drive R&d-Based Process Expansion
Samrat Mukherjee, Shekhar Viswanath, Jeffrey Breting
5:40 PMApplication of Agent Technique in Bioprocess Modelling for Plant-Wide Process Improvement
Ying Gao, Katie Kipling, Jarka Glassey, Yuhong Zhou, Mark Willis, Gary Montague, Nigel Titchener-Hooker

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